uworld/amboss Flashcards
what is Drug Reaction Eosinophilia Systemic Symptoms(DRESS SYNDROME)
drug rxn 2-8wks after drug exposure. (fever, lymphadenopathy, facial edema) rash
drugs that causes DRESS SYNDROME
phenytoin, carbamazepine, allopurinol, sulfasalazine, minocycline, vanco
Cutaneous neurofibroma are composed of what cells
Schwann cells
Methadone can cause what type of heart problem
Qt prolongation/torsade
what’s the cause of normal age related diminished antibody response to infections/vaccinations
Immunosenscense(Decrease PRODUCTION of naive B& T lymphocytes.
Mutation in TTN(titin) gene is ass w/ what heart problem
DIALATED CARDIO
SS of Dandy walker/ CT
non-communicating HYDROCEPHALUS. on CT lack of VERMIS(blk spot on the bk of the head)
what type of saline do you give for hypovolemia/shock
0.9%(normal saline) Lactated ringer solution
Symptoms/presentation/microscopy of AVM pts
seisures/headaches. Blood does not pass thru capillary bed. TANGLE of lrg blood vessels in THICKENED walls
Osteoprogrin does what to OSTEOCLAST/ RANK-L
inhibs osteoclast/ prevents RANK-L from binding to RANK
DOC/MOA for scabies
Permethrin(inhib Na+)
alternative drug Ivermectin(inhib CL-)
what nerve is effected when it’s compress due to obesity/tight clothing
Lateral Femoral Cutaneous nerve
what’s a value that’s normal in CO poisoning/anemia/polycythemia
partial pressure of O2 in he blood(PO2)
what supplies the papillary muscle
RCA-PDA(post. descending art)
thru what mechanisim is Vancomycin resistant
Transposition(plasmid encoded) alteration of peptidoglycan synthesis
what are the cancers that releases PTHrP
renal, bladder, ovarian, squamous cell of head neck, lung.
PTHrP does NOT simulate 25D to 1,25 so lvls will be low
what’s the cause of Anencephaly & what kind of hydramniosis will you see
failure of rostral neuropore to close. Hole in the head(absence of forebrain) cannot swallow (POLYHYDRAMNIOSIS)
Sudden painless loss of vision is called/cause
central retina art. occlusion/ thrombosis, vasculitis, fibromuscular dysplasia. Do a carotid art. ultrasonography
what respiratory problem can an immature infant hv w/ mechanical ventilation use
BRONCHOPULMONARY DYSPLASIA
what’s a SE(ion) of albuterol
HYPOKALEMIA
where is Hormone sensitive lipase found
adipose mobilized triglycerides in FFA /glycerol. FFA to acetyl-coA=Ketone bodies(gluconeogenesis)
describe orphan Annie eye/what cancer
Lrg cell w/ nuclei containg finely dispersed chromatin/intranuclear inclusions. PAPILLARY CARCINOMA (MC)
what contributes to the Hyperglycemia in glucocorticoids use
increase in epression of liver enzymes(gluconeogenesis)
what enzyme converts Testosterone to DHT
5a reductase
how does pts w/5a reductase def present
Phenotypically/karyotipically male but FEMALE external(sml phallus,hypospadias)
SYMPTOMS OF VIPOMA
Watery Dia, Achylodria, Hypokalemia
what does Radioactive Iodine uptake measures(RAIU)
Organification of Iodine & synthesis of NEW (ENDOGENOUS) thyroid hormone
what’s the level of RAIU inEXOGENOUS (hypothyroid drugs prescriptions)
Low because RAIU measures ENDOGENOUS thyroid
what’s the level of RAIU in Gaves
INCREASE cuz ur mkng the Thyroid hormone
What’s the levels for GnRH, LH, Testosterone in a prolactinoma
all decrease Tumors don’t follow -fdbk
what is the Na+ level in Hyperaldosteronism(conn syndrome)
Normal due to aldosterone escape but HYPOKALEMIA/METABOLIC ALKALOSIS
