wk 8 review

Question 1

Which of the following statements is not true concerning testing for drugs of abuse?
- A two-tired testing approach includes screening and confirmatory testing
- Confirmatory testing must use methods with high specificity and low sensitivity
- Screening tests detect classes of drugs
- GC-MS is the reference method used for confirmation

Answer 1

Confirmatory testing must use methods with high specificity and low sensitivity

Question 2

True or false
Common routes of exposure to toxins are through the gastrointestinal tract, lungs, and skin.

Answer 2

true

Question 3

Which of the following is not true concerning analysis of toxic agents?
- Screening tests have good specificity but lack sensitivity
- Confirmatory tests report the concentration of the analyte
- Screening tests are a rapid test intended to detect the presence of a substance
- The reference method for most compounds is gas chromatography with a mass spectrometer (GC-MS)

Answer 3

Screening tests have good specificity but lack sensitivity

Question 4

Toxic levels of acetaminophen are associated with
- Ototoxicity
- nephrotoxicity
- hepatotoxicity
- neurotoxicity

Answer 4

hepatotoxicity

Question 5

Pharmacokinetics and drug concentration are influenced by which of the following factors?

Answer 5

Absorption, distribution, excretion, metabolism

Question 6

A drug’s most direct and effective method of delivery to its site of action is:
- Oral administration
- Intramuscular injection
- Intravenous administration
- Aerosol ingestion

Answer 6

Intravenous administration

Question 7

A blood draw to determine a peak level of a drug should be drawn:
- One hour after an orally administered dose
- Immediately after drug administration
- 90 minutes after an orally administered dose
- Immediately before drug administration

Answer 7

One hour after an orally administered dose

Question 8

True or False
Cytochrome P450 is an enzyme that influences the effectiveness of a drug in an individual.

Answer 8

true