wk 3 review Flashcards
Pathological condition in which the proximal tubules in the kidneys do not reabsorb glucose, amino acids, uric acids, and bicarbonates resulting in their loss to the urine concentrate.
- lesch-Nyhan syndrome
- gout
- congestive heart failure
- fanconi syndrome
fanconi
Given the following information, calculate the creatinine clearance:
Urine creatinine: 87 mg/dL
Plasma creatinine: 3.2 mg/dL
Urine volume for 24 hours: 810 mL
Patient BSA: 1.92
- 13.7
- 11.05
- 14.25
- 10.53
13.7
Given the following results, determine if the patient is experiencing azotemia and what kind.
BUN: 56 mg/dL
Creatinine: 2.1 mg/dL
- normal kidney function
- pre renal azotemia
- renal azotemia
- post renal azotemia
pre-renal (27:1)
- pre-renal: >20:1
- intrarenal: <10:1
- post renal: 10-20:1
Which of the following serves as the glomerular filtration rate for clinicians?
- urea
- creatinine
- uric acid
- ammonia
creatinine
What does an increase in serum enzyme levels indicate?
- decreased enzyme catabolism
- accelerated enzyme production
- tissue damage and necrosis
- increased glomerular filtration rate
tissue damage and necrosis
When measuring enzyme activity, if the instrument is operating at 50 C lower than the temperature prescribed for the method, how would the results be affected?
- lower than expected
- higher than expected
- varied, showing no pattern in results
- all would be clinically abnormal
lower than expected
true or false
The following statement could be used to describe zero-order kinetics:
Substrate is present in excess, rate of reaction is constant with time and dependent only on the concentration of enzyme in the system.
true
These type of inhibitors may allow substrate binding but will inhibit the formation of product.
- competitive inhibitors
- non-competitive inhibitors
- uncompetitive inhibitors
- all inhibitors do this
non-competitive
