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clinical chem 1 > exam 3 bingo > Flashcards

exam 3 bingo Flashcards

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1
Q

the major transporter of drugs

A

albumin

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2
Q

The phenomenon in which a drug is metabolized and results in a reduced concentration of the drug before reaching the circulatory system

A

first pass effect

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3
Q

The study of the biochemical and physiological effects of drugs and their mechanisms of actions

A

pharmacodynamics

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4
Q

this tumor marker often is measured in both the total and free form

A

PSA

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5
Q

The concentration range of a drug within which the drug produces the desired effect

A

therapeutic range

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6
Q

This tumor marker is primarily used as a marker for ovarian cancer

A

CA-125

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7
Q

This is found as a contaminant of homemade liquors and can cause optic neuropathy

A

methanol

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8
Q

this is a significant environmental pollutant and is easily taken up by crops

A

cadmium

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9
Q

This is a cardioactive drug that is used to treat arrythmias and CHF. Biotin is known to interfere with this test

A

digoxin

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10
Q

the most direct and effective route of administration of drug

A

IV

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11
Q

This is a common malignant tumor in kids associated with high levels of plasma, epinephrine, norepinephrine and dopamine

A

neuroblastoma

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12
Q

This test is used along with hCG to classify nonseminomatous tumor

A

AFP

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13
Q

This is a kind of testing method that can be performed on solid tissue tumor markers

A

immunohistochemistry

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14
Q

the predicted dose that would produce a toxic response in 50% of the pop

A

TD50

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15
Q

This may occur when analyte concentrations exceed the analytical range excessively

A

hook effect

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16
Q

this drug is the hepatic metabolite of procainamide

A

NAPA

17
Q

the study of the movement of drugs in the body

A

pharmacokinetics

18
Q

this drug is commonly tested for both total and free forms

A

phenytoin

19
Q

endogenous substances biologically synthesized either in living cells or in microorganisms

A

toxins

20
Q

This method of analysis of toxic agent has good sensitivity but lacks specificity

A

screening

21
Q

These types of tumor markers are valuable in diagnosing neuroblastomas, pituitary and adrenal adenomas

A

endocrine tumor markers

22
Q

This tumor marker is the prototypical oncofetal antigen and is used for monitoring colorectal cancer

A

CEA

23
Q

Uses the results from animal experiments to predict what level of exposure will cause harm to humans

A

descriptive toxicology

24
Q

This is a metal with 3 forms, one of which is liquid at room temp

A

mercury

25
Q

This is a useful system to compare relative toxicities of substances as the predicted endpoint is death

A

dose-response relationship

26
Q

B-macroglobulin and immunoglobulins are part of this group of tumor markers

A

serum protein tumor markers

27
Q

Chemicals and drugs that are not normally found in or produced by the body

A

xenobiotics

28
Q

trace element free tube

A

royal blue top

29
Q

This is an example of something that can have significant interference in immunoassays by cross-linking with the capture/label antibody

A

HAMA

30
Q

This drug is ototoxic enough that it is recommended that baseline audiology testing is performed

A

tobramycin

31
Q

This type of tumor marker can help to choose between endocrine and cytotoxic therapies

A

receptor tumor marker

32
Q

what test can be performed to determine if the fluid from a patients nose is sinus or spinal fluid

A

beta-transferin

33
Q

Positive drug screens for this type of substance has wide cross-reactivity with common OTC medications.

A

Amphetamines/Methamphetamines

34
Q

This tumor marker is a modified Lewis blood group antigen.

A

Carbohydrate antigen 19-9 (CA 19-9)

clinical chem 1 (23 decks)

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