lipids Flashcards
high lvls of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis
- chylomicrons
- VLDL
- LDL
- HDL
HDL
which of the following lipid results would be expected to be falsely elevated on a serum specimen from a non-fasting patient?
- cholesterol
- triglyceride
- HDL
- LDL
triglyceride
Turbidity in serum suggests elevation of:
- total protein
- albumin
- cholesterol
- chylomicrons
chylomicrons
The function of the major lipid components of the very-low density lipoproteins (VLDL) is to transport
- cholesterol from the peripheral cells
- cholesterol and phospholipids to peripheral cells
- exogenous triglycerides
- endogenous triglycerides
endogenous triglycerides
lipoprotein structure
spherical formation of lipids and proteins for delivery of internal cargo
what do chylomicrons transport and to where
exogenous triglycerides to the liver (adipose tissue)
apolipoprotein marker for chylomicrons
Apo B-48
describe VLDL
- what it transports
- where it is made
- apolipoprotein marker
- endogenous triglycerides during fasting state
- made in liver
- Apo b-100, E, C-2, C-3
descibe LDL
- what it transports
- how it is made
- made from VLDL w/in blood circulation
- transports cholesterol from liver to organs
how can LDL damage cells
OX reaction as it passes cell walls damages cells, allowing other LDL to adhere and buildup plaque
describe HDL
- what it transports
- where it is made
- made by liver and intestines
- reverse cholesterol transport
- removes excess LDL from cells
what diseases is lipoprotein X seen in
- biliary cirrhosis
- cholestasis
list the 4 main lipid metabolism pathways
- absorption
- exogenous
- endogenous
- reverse cholesterol
describe the absorption lipid metabolism pathway
dietary lipids are recived and broken down by amylase and converted to monosaccharides to pass through intestinal microvilli
describe the exogenous lipid metabolism pathway
after passing through intestine food material is packed into chylomicrons to transport to liver via LPL
describe the endogenous lipid metabolism pathway
pdt from liver into VLDL which is converted to LDL
- LPL absorbed by macros or HDL
describe reverse cholesterol lipid metabolism pathway
peripheral cells remove lipids to maintain cholesterol via HDL
how is LDL measured
total cholesterol-HDL-(triglycerides/5)
what is arteriosclerosis
general name for arteries becoming thick and stiff due to plaque
how is LDL determined
total chol-HDL-(trig/5)
HDL RR
40-75 mg/dL
LDL RR
50-130 mg/dL
total cholesterol RR
140-200 mg/dL
triglyceride RR
60-150 mg/dL
