lipids Flashcards

1
Q

high lvls of which lipoprotein class are associated with decreased risk of accelerated atherosclerosis
- chylomicrons
- VLDL
- LDL
- HDL

A

HDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

which of the following lipid results would be expected to be falsely elevated on a serum specimen from a non-fasting patient?
- cholesterol
- triglyceride
- HDL
- LDL

A

triglyceride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Turbidity in serum suggests elevation of:
- total protein
- albumin
- cholesterol
- chylomicrons

A

chylomicrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The function of the major lipid components of the very-low density lipoproteins (VLDL) is to transport
- cholesterol from the peripheral cells
- cholesterol and phospholipids to peripheral cells
- exogenous triglycerides
- endogenous triglycerides

A

endogenous triglycerides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

lipoprotein structure

A

spherical formation of lipids and proteins for delivery of internal cargo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what do chylomicrons transport and to where

A

exogenous triglycerides to the liver (adipose tissue)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

apolipoprotein marker for chylomicrons

A

Apo B-48

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

describe VLDL
- what it transports
- where it is made
- apolipoprotein marker

A
  • endogenous triglycerides during fasting state
  • made in liver
  • Apo b-100, E, C-2, C-3
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

descibe LDL
- what it transports
- how it is made

A
  • made from VLDL w/in blood circulation
  • transports cholesterol from liver to organs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how can LDL damage cells

A

OX reaction as it passes cell walls damages cells, allowing other LDL to adhere and buildup plaque

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

describe HDL
- what it transports
- where it is made

A
  • made by liver and intestines
  • reverse cholesterol transport
  • removes excess LDL from cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what diseases is lipoprotein X seen in

A
  • biliary cirrhosis
  • cholestasis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

list the 4 main lipid metabolism pathways

A
  • absorption
  • exogenous
  • endogenous
  • reverse cholesterol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

describe the absorption lipid metabolism pathway

A

dietary lipids are recived and broken down by amylase and converted to monosaccharides to pass through intestinal microvilli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

describe the exogenous lipid metabolism pathway

A

after passing through intestine food material is packed into chylomicrons to transport to liver via LPL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

describe the endogenous lipid metabolism pathway

A

pdt from liver into VLDL which is converted to LDL
- LPL absorbed by macros or HDL

17
Q

describe reverse cholesterol lipid metabolism pathway

A

peripheral cells remove lipids to maintain cholesterol via HDL

18
Q

how is LDL measured

A

total cholesterol-HDL-(triglycerides/5)

19
Q

what is arteriosclerosis

A

general name for arteries becoming thick and stiff due to plaque

20
Q

how is LDL determined

A

total chol-HDL-(trig/5)

21
Q

HDL RR

A

40-75 mg/dL

22
Q

LDL RR

A

50-130 mg/dL

23
Q

total cholesterol RR

A

140-200 mg/dL

24
Q

triglyceride RR

A

60-150 mg/dL