Wk 25 - Commonly prescribed drugs 3 Flashcards
1
Q
Which NSAIDs have the most favourable thrombotic cardiovascular safety profiles?
A
Naproxen + low dose ibuprofen
2
Q
When would you not prescribe etoricoxib?
A
BP above 140/90mmHg + inadequately controlled
3
Q
Ferrous sulphate
A
- HB conc should rise 2g/100ml over 3-4 wks
- Once normal, continue for 3 months
- GI irritation
- Constipation in elderly
4
Q
What is the MHRA advice on finasteride?
A
- Depression + suicidal thoughts for male pattern hair loss
- Depression for benign prostatic hyperplasia
- STOP
5
Q
What are the important points to remember when taking finasteride?
A
- Excreted in semen tf use condom
- Childbearing should avoid handling crushed + broken tabs
- Reports of breast cancer: nipple discharge, lumps + pain
6
Q
When taking furosemide, what should be monitored?
A
Renal + electrolyte abnormalities
7
Q
When would furosemide in older people be inappropriate?
A
- 1st line HPT
- HPT w/ concurrent urinary incontinence
- Dependent ankle oedema w/o evidence of HF, liver failure, nephrotic syndrome or renal failure
8
Q
What electrolyte disturbance can occur when taking furosemide?
A
- Hypokalaemia
- Esp w/ cardiovascular disease or treated w/ cardiac glycosides
- Potassium-sparing diuretics avoid need to take suppliments
9
Q
Other than hypokalaemia, what else does loop diuretics cause?
A
- Urinary retention if there is an enlarged prostate
- Adequate urinary output before initiating treatment
10
Q
What are the safety issues of gabapentin?
A
- Risk of severe respiratory depression even w/o concomitant opioid med
- Respiratory or neurological disease, renal impairment, concomitant use of CNS depressant + elderly = higher risk
