Why Might my Patient be Jaundiced ? Part 2 Flashcards

1
Q

Where is the main site of break down of red blood cells?

A

The spleen

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2
Q

What is a normal by-product of the breakdown of red blood cells

A

Bilirubin

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3
Q

What is bilirubin used to form ? Where does this occur?

A

Bile in the liver

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4
Q

Describe the biliary tree

A

A set of tubes connecting the liver tot the 2nd part of the duodenum

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5
Q

What 3 structures make up the interlobular portal triad?

A

branch of the Hepatic vein, branch of the hepatic artery and a biliary duct

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6
Q

What is the biliary tree made up of? What do they do?

A

A number of ducts which transport bile

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7
Q

What forms the common hepatic duct

A

Right and left hepatic ducts

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8
Q

What unite to form the bile duct

A

Common hepatic duct and the cystic duct

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9
Q

Where does the bile duct drain into?

A

The second part of the duodenum

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10
Q

Where is the location of the bile duct?

A

Descends posteriorly to the 1st part of the duodenum

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11
Q

Where does the bile duct travel into?

A

A groove on the posterior aspect of the pancreas where it then joins with the main pancreatic duct to form the ampulla

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12
Q

Where does the bile duct and the main pancreatic duct drain into?

A

The 2nd part of the duodenum through the major duodenal papilla

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13
Q

Name the 3 sphincters related to the bile duct

A

Bile duct sphincter, pancreatic duct sphincter and the sphincter of Oddi

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14
Q

What investigation is used to study the biliary tree and the pancreas?

A

ERCP (Endoscopic Retrograde Cholangiopancreatography)

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15
Q

What could happen to the levels of bilirubin if there was an abstruction somewhere in the biliary tree?

A

Backflow of bile up to the liver.

Overspill of bile into the blood including bilirubin

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16
Q

What can cause an obstruction of the biliary tree?

A

Gallstones and carinoma at head of pancreas

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17
Q

Describe the panceras

A
Head with uncinate process
Neck 
Body 
Tail
Retroperitoneal organ which lies transversely across the posterior abdomen
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18
Q

What surrounds the head of the pancreas?

A

The duodenum

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19
Q

What is the endocrine function of the pancreas?

A

Islets of Lannerghans (insulin and glucagon into the bloodstream)

20
Q

What is the exocrine function of the pancreas?

A

Acinar cell (pancreatic digestive enzymes into main pancreatic duct)

21
Q

Where does the pancreas branch from?

A

Mainly from the splenic artery (pancreatic branches)

22
Q

What is the most common cause of pain in the pancreas?

A

Pancreatitis

23
Q

What is a cause of pancreatitis

A

Blockage of the ampulla by a gallstone causing bile to to be diverted into the pancreas leading to irritation and inflammation

24
Q

Describe the type of organ the pancreas is

A

Foregut and midgut organ

25
Q

Where can pancreatic pain present?

A

In the epigastric region / umbilical region

Radiate through to the back

26
Q

What parts of the duodenum are foregut organs?

A

1st and 2nd parts of the duodenum

27
Q

What are the rest of the small intestines?

A

Midgut organs

28
Q

What are the 4 parts of the duodenum?

A

Superior
Descending
Horizontal
Ascending

29
Q

What sphincter does the duodenum begin at?

A

Pyloric sphincter

30
Q

What does the pyloric sphincter control?

A

The flow of chyme from the stomach to the duodenum

31
Q

What is secreted by the duodenum

A

A number of peptide hormones into the blood (gastrin and CCK)

32
Q

Where does pain from a duodenal ulcer tend to present?

A

Epigastric region

33
Q

What does the close relationship between the pancreas and the duodenum cause?

A

Similarities in the blood supply

34
Q

What is one of the branches of the gastroduodenal artery?

A

Superior pancreaticoduodenal

35
Q

What is one of the brances of the superior mesenteric artery?

A

Inferior pancreaticodudoenal

36
Q

What makes up most of the small intestines?

A

Jejunum and the ileum

37
Q

Where does the jejunum begin?

A

At the duodenaljejunal flexure

38
Q

Where does the ileum end?

A

At the ileocacal junction

39
Q

Describe the folds in the jejunum?

A

Mucosa is highly folded
The folds are called plicae circularis
Slightly rough in texture

40
Q

Is the mucosa of distal ileum smoother or rougher than the proximal end?

A

Smoother

41
Q

What does bile help with?

A

The absorption of fats form the GI tract lumen into the intestinal cells

42
Q

Where are fats absorbed from and where do they go?

A

From the intestinal cells and into specialised lymphatic vessels of the small intestine called lacteals

43
Q

Where do fats eventually drain into the venous system at?

A

At the left venous angle

44
Q

Where do lymph vessels lie in the abdomen?

A

Alongside arteries

45
Q

What are the main 4 groups of lymph nodes drainign abdominal organs?

A

Celiac (foregut)
Superior mesenteric (midgut)
Inferior mesentric (hinf
Lumbar (kidneys, pelvis)

46
Q

Where does the right lymphatic duct drain into?

A

DeeThe right venous angle (angle between the right subclavian and right internal jugular veins

47
Q

Where does the thoracic duct drain lymph into?

A

Into the left venous angle (angle between the left subclavian and left interanal jugual veins