Histology of the GI Tract Flashcards

1
Q

What covers the oral cavity, oropharynx and laryngopharynx

A

Stratified squamous epithelium

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2
Q

What covers the nasal cavity and the nasopharynx

A

Respiratory epithelium

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3
Q

What covers the anterior 2/3rd of the tongue

A

Stratified squamous epithelium

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4
Q

What covers the posterior 1/3rd of the tongue

A

Smooth stratified squamous epithelium

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5
Q

Name the 4 types of papillae on the tongue

A

Fungiform
Circumvallate
Foliate
Filiform

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6
Q

Describe the filiform

A

They have no taste buds

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7
Q

Describe the fungiform

A

Strawberry pips - lots of taste buds

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8
Q

Describe the foliate

A

Little slits, lined by taste buds- largest surface area due to the presence of slits

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9
Q

Describe the circumvallate

A

Obvious growth structures - serous glands

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10
Q

What 4 major layers compose the stereotypical GI tract?

A

Mucosa
Submucosa
Muscularis Externa
Serosa / Adventitia

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11
Q

What are the 3 parts of the mucosa

A

Epithelium
Lamina propria
Muscularis mucosae

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12
Q

What comprises the submucosa

A

Loose connective tissue

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13
Q

What comprises the muscularis externa

A

Two thick layers of smooth muscle, an inner cicrular layer and an outer longitudinal layer

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14
Q

What comprises the serosa or adventitia

A

Outer layer of connective tissue that either suspends the digestive tract or attaches it to other organs.

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15
Q

What is the difference between serosa and adventitia

A

Serosa - something you can pick up such as the stomach.

The adventitia is something that is more bound down eg the oesophagus

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16
Q

Describe the change in cells at the gastro-oesophageal junction

A

Abrupt transition from stratified squamous epithelium of the oesophagus to the columnar epithelium of the cardia of the stomach

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17
Q

What does 1 gastric pit branch into

A

1-7 gastric glands

18
Q

What are the gastric pits lined by?

A

Surface mucous cells

19
Q

What are the types of mucosa that can be found in the stomach

A

Cardia (deep gastric pits that branch into loosely packed tortuous glands)
Body (shallow gastric pits with long straight gastric glands)
Pylorus (deep gastric pits with branched, coiled gastric glands at a higher density than in the cardia

20
Q

Why is the muscularis externa of the stomach unusual?

A

It contains an additional layer - it is oblique to the usual circular and longitudinal muscle layers and is located internal to the circular layer. This layer aids the churning action of the stomach

21
Q

What is the thickened inner circular layer of smooth muscle?

A

Pyloric sphincter

22
Q

What are the pits in the small intestine called?

A

Crypts of Lieberkuhn

23
Q

Describe the length of the duodenum in terms of its different components

A

Duodenum (25cm)
Jejunum (2m)
Ileum (2.75m)

24
Q

What type of glands can be found in the duodenum

A

Brunner’s glands

25
What is the name of the specialised lymphoid follicles in the ileum
Peyer's patches
26
Where is the plicae circularis found?
Jejunum
27
What is the function of enterocytes
Absorptive cell
28
What is the function of Goblet cells
Produce mucin for protection and lubrication
29
What is the function of paneth cells
Defensive function and a regulating role in bascterial flora
30
What is the function of neuroendocrine cell
Produce hormones
31
What is the function of stem cells
Divide to replenish the epithelium
32
Where are fats deposited
In the lacteal
33
How are Brunner's glands stimulated
With the presence of chyme
34
What do Brunner's glands produce when stimulated
thin, alkaline, mucous to neutralise the chyme
35
What do the colonic glands or the colonic crypts produce
Mucus
36
What are the two principle types of cells in the Large intestine
Absorptive and goblet cells
37
How are the cells in the large intestine arranged
In straight, tubular glands referred to as crypts that extend down the muscularis mucosae
38
Describe the longitudinal smooth muscle in the large intestine
Not continuous | found in 3 muscular strips called teniae coli
39
What is the name of the guts nervous system
Enteric nervous system
40
Where does the ENS receive input from
The autonomic nervous system
41
What else helps to regulate the secretion in the epithelium?
The second netowrk of neurones in the submucosa (submucosal plexus)