Why Are Hormones Important? Flashcards
Autocrine
Released by cells & have a local effect on same cells type from which chemical signals were released.
Paracrine
Released by cells & affect other cell types locally without being transported in the blood.
Neurotransmitter
Produced by neurons & secreted into extracellular spaces by presynaptic nerve terminals; travels short distances, influences post-synaptic cells.
Hormone Secretion: Acute
Sudden release of hormones due to stimulus (eg. adrenaline in response to stress).
Hormone Secretion: Chronic
Small variations over a long period of time (eg. thyroid hormones).
Episodic
Oestrogen or progesterone produced during menstrual cycle.
Why do target cells respond to a hormone?
The target cells have the correct receptor to respond to the hormone.
AP Hormones
FSH, LH, ACTH, thyroid hormone, prolactin, GH, MSH.
PP Hormones
ADH, oxytocin.
Tropic Hormones
Stimulate secretion of other hormones from target tissues.
Non-Trophic Hormones
Initiates an effect from a target tissue.
Hormone Secretion from PP
Stimuli causes neurons in hypothalamus to increase or decrease AP frequency. APs conducted along neurons from hypothalamus to PP. Axon terminals of these neurons store hormones which are secreted into circulatory system to the target tissue.
Hormone Secretion from AP
Stimuli within NS regulates secretion of releasing hormones from neurons in hypothalamus. Releasing hormones pass to AP, stimulating release of hormones from AP. These travel in the bloodstream to reach target tissue. Target tissue may be another gland.
Thyroid Gland
Highly vascular. Only gland that stores its own hormones. Its hormones increase rate of metabolism.