White Blood Cells - REVIEW DAY OF Flashcards

1
Q

examples of granulocyte cells

A
  • neutrophils
  • band forms
  • eosinophils
  • basophils
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2
Q

neutrophils also called

A
  • PMNs
  • polys
  • segs
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3
Q

the most common white cell is

A
  • neutrophils
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4
Q

band forms also called

A
  • stabs
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5
Q

band forms represent

A
  • immature PMNs
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6
Q

which is the most uncommon of all granulocytes

A
  • basophils
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7
Q

what is the largest white cell normally found in periphery

A
  • monocyte
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8
Q

what to do when the WBC is too high or too low

A
  • order a WBC differential
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9
Q

things that can cause neutrophilia

A
  • CML
  • leukocyte adhesion deficiency
  • physiologic
  • acute infections
  • acute inflammation
  • drugs
  • smoking

CPLAADS

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10
Q

physiologic causes of neutrophilia

A
  • exercise
  • pregnancy
  • lactation
  • neonates
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11
Q

drugs that cause neutrophilia

A
  • corticosteroids

- G-CSF

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12
Q

most common cause of neutrophilia

A
  • smoking
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13
Q

things that cause neutropenia

A
  • physiologic
  • drugs
  • chemotherapeutic agents
  • immune

DICP

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14
Q

physiologic causes of neutropenia

A
  • in African Americans
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15
Q

drugs that cause neutropenia

A
  • anti-psychotics
  • anti-epileptics
  • anti-thyroid
  • antibiotics

PETA

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16
Q

immune causes of neutropenia

A
  • lupus

- rheumatoid arthritis

17
Q

what is agranulocytosis

A
  • absence or near complete absence of neutrophils in the peripheral blood
18
Q

platelet count of agranulocytosis

19
Q

hemoglobin of agranulocytosis

20
Q

agranulocytosis is almost always related to

21
Q

drugs that induce agranulocytosis

A
  • clozapine
  • propythiouracil
  • anti-convulsants
  • sulfa and chloramphenicol
  • levamisol-contaminated cocaine

SLAPC

22
Q

what does agranulocytosis cause

A
  • severe necrotizing ulcers in the mouth and throat

- severe risk for life-threatening infection

23
Q

differential diagnosis of eosinophilia

A
  • neoplasm
  • allergy/asthma
  • addision’s, athero-embolic disease
  • collagen vascular disease
  • parasites

NAACP

24
Q

causes of basophilia

A
  • myeloproliferative disorders
  • hypersensitive reactions
  • thyroid disease

HTM

25
causes of lymphocytosis
- viral and bacterial infections - chronic lymphocytic leukemia VBC
26
causes of lymphopenia
- immunodeficiencies - immunosuppressive drugs - lymphomas - granulomatous diseases GILI
27
immunodeficiencies that can cause lymphopenia
- HIV/AIDS
28
immunosuppressive drugs that can cause lymphopenia
- corticosteroids
29
granulomatous diseases that cause lymphopenia
- sarcoid | - TB
30
cause of monocytosis
- myelodysplastic syndrome - infections (bacterial, protozoal, rickettsial) - leukemias - MIL
31
acquired defects in neutrophil function
- corticosteroid use - alcoholism - leukemias - myelodysplasia - myeloproliferative disorders CALMM
32
inherited neutrophil abnormalities
- LAD - CGD - Myeloperoxidase deficiency - Chediak Higashi syndrome LCMC