White Blood Cells - REVIEW DAY OF Flashcards
examples of granulocyte cells
- neutrophils
- band forms
- eosinophils
- basophils
neutrophils also called
- PMNs
- polys
- segs
the most common white cell is
- neutrophils
band forms also called
- stabs
band forms represent
- immature PMNs
which is the most uncommon of all granulocytes
- basophils
what is the largest white cell normally found in periphery
- monocyte
what to do when the WBC is too high or too low
- order a WBC differential
things that can cause neutrophilia
- CML
- leukocyte adhesion deficiency
- physiologic
- acute infections
- acute inflammation
- drugs
- smoking
CPLAADS
physiologic causes of neutrophilia
- exercise
- pregnancy
- lactation
- neonates
drugs that cause neutrophilia
- corticosteroids
- G-CSF
most common cause of neutrophilia
- smoking
things that cause neutropenia
- physiologic
- drugs
- chemotherapeutic agents
- immune
DICP
physiologic causes of neutropenia
- in African Americans
drugs that cause neutropenia
- anti-psychotics
- anti-epileptics
- anti-thyroid
- antibiotics
PETA
immune causes of neutropenia
- lupus
- rheumatoid arthritis
what is agranulocytosis
- absence or near complete absence of neutrophils in the peripheral blood
platelet count of agranulocytosis
- normal
hemoglobin of agranulocytosis
- normal
agranulocytosis is almost always related to
- drugs
drugs that induce agranulocytosis
- clozapine
- propythiouracil
- anti-convulsants
- sulfa and chloramphenicol
- levamisol-contaminated cocaine
SLAPC
what does agranulocytosis cause
- severe necrotizing ulcers in the mouth and throat
- severe risk for life-threatening infection
differential diagnosis of eosinophilia
- neoplasm
- allergy/asthma
- addision’s, athero-embolic disease
- collagen vascular disease
- parasites
NAACP
causes of basophilia
- myeloproliferative disorders
- hypersensitive reactions
- thyroid disease
HTM
causes of lymphocytosis
- viral and bacterial infections
- chronic lymphocytic leukemia
VBC
causes of lymphopenia
- immunodeficiencies
- immunosuppressive drugs
- lymphomas
- granulomatous diseases
GILI
immunodeficiencies that can cause lymphopenia
- HIV/AIDS
immunosuppressive drugs that can cause lymphopenia
- corticosteroids
granulomatous diseases that cause lymphopenia
- sarcoid
- TB
cause of monocytosis
- myelodysplastic syndrome
- infections (bacterial, protozoal, rickettsial)
- leukemias
- MIL
acquired defects in neutrophil function
- corticosteroid use
- alcoholism
- leukemias
- myelodysplasia
- myeloproliferative disorders
CALMM
inherited neutrophil abnormalities
- LAD
- CGD
- Myeloperoxidase deficiency
- Chediak Higashi syndrome
LCMC