Intro to Medical Oncology Flashcards
fine needle aspiration is good for
- carcinomas
excisional biopsy definition
- surgical procedure that removes the entire suspected area
excisional biopsy good for
- melanoma treatment/diagnosis
- lymphoma diagnosis
6 hallmarks of cancer
- sustaining proliferative signaling
- evading growth suppressors
- activating invasion and metastasis
- enabling replicative immortality
- inducing angiogenesis
- resisting cell death
4 additional hallmarks of cancer
- deregulating cellular energetics
- avoiding immune detection
- tumor promoting inflammation
- genome instability and mutation
nonspecific chemotherapy may be more effective given as
- a bolus dose
toxic effects of nonspecific chemotherapy expressed during
- any attempt at cell division
cell cycle specific chemotherapy effect exerted when
- dividing cells only
administration of cell cycle specific chemotherapy
- continuous infusion
- multiple divided doses
examples of nonspecific chemotherapeutic agents
- alkylating agents
- anthracyclines
- platinum agents
examples of cell cycle specific chemotherapeutic agents
- antimetabolites
- vincas
- taxanes
- topoisomerase inhibitors
primary treatment; intended to cure is
- definitive
treatment given to relieve symptoms and reduce suffering is
- palliative
therapy given after a cancer has not responded to other treatments is
- salvage
therapy given prior to the primary therapy is
- neoadjuvant