Week 9: Urothelial Neoplasms and Wilms Tumor Flashcards

1
Q

ID

A

Papilloma

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2
Q

ID

A

Invasive Papilloma

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3
Q

ID

A

Flat noninvasive carcionoma in situ (CIS)

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4
Q

ID

A

flat invasive

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5
Q

Genetic cause of noninvasive papillary tumors

A

Amplification of FGFR3, activating mutation in RAS

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6
Q

Genetic cause of Flat noninvasive urothelial carcinoma in situ (CIS)

A

disrupted function of p53 and RB (tumor supressor gene)

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7
Q

ID

A

Urothelial Papilloma - retained umbrella cells and fibrovascular cores

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8
Q

ID

A

Low-Grade Papillary Urothelial Carcinoma

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9
Q
A

High-grade papillary urothelial carcinoma

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10
Q

ID

A

Low vs. High-grade papillary urothelial carcinoma

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11
Q

ID

A

Urothelial Carcinoma In Situ (CIS) (Flat Urothelial Carcinoma

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12
Q

ID

A

Invasive Urothelial Carcinoma

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13
Q

ID

A

plasmacytoid - high risk variant of Invasive Urothelial Carcinoma

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14
Q

ID

A

Micropapillary - high risk variant of Invasive Urothelial Carcinoma

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15
Q

ID - Right

A

Nephrogenic rest in Wilm’s Tumor

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16
Q

ID

A

Wilm’s Tumor

17
Q

ID

A

Anaplasia - hyperchromic, pleomorphic nuclei (3X bigger)

18
Q

ID

A

Anirida - in Syndromic Wilm’s Tumor WAGR Syndrome