Lab 2: Lymphomas Flashcards
ID
Hodkin Lymphoma; Reed-Sternberg cells
What cell markers do you see with Hodkin Lymphoma?
ID
Follicular Lymphoma
What translocation is present in Follicular Lymphoma
t(14;18) IgH and anti-apoptotic BCL-2
is anti-apoptotic and proto-oncogene indolent or aggressive?
anti-apoptotic are indolent
proto-oncogene are aggressive
ID
Small Lymphocytic Lymphoma
What cell markers do you see with Small Lymphocytic Lymphoma
is Small Lymphocytic Lymphoma indolent or aggressive
indolent
What causes Small Lymphocytic Lymphoma to develop to Diffuse-Large B-Cell Lymphoma (DLBCL)
Richter transformation; also happens with Chronic Lymphocytic Leukemia (CLL)
ID
Diffuse-Large B-Cell Lymphoma (DLBCL)
What cell markers do you see with Diffuse-Large B-Cell Lymphoma (DLBCL)
ID
ID
Burkitt Lymphoma
What translocation is present in Burkitt Lymphoma
t(8;14) c-MYC and IgH
What is seen in endemic versus sporadic Burkitt Lymphoma
Endemic - jaw mass linked with EBV
Sporadic - mass in ileocecum and peritoneum