Week 7: Lung Tumors and Molecular Testing Flashcards
1
Q
cancers highly associated with smoking
A
squamous and small cell carcinoma
2
Q
most common transcription factor immunohistochemical stains in squamous cell carcinoma
A
p40 and p63
3
Q
most common mutation in squamous cell carcinoma
A
CDKN2A and TP53
4
Q
ID
A
Squamous Cell Carcinoma
5
Q
ID
A
squamous metaplasia
6
Q
ID
A
carcinoma in-situ high-grade dysplasia
7
Q
ID
A
low-grade dysplasia
8
Q
ID
A
Squamous Cell Carcinoma
9
Q
most common mutations in adenocarcinoma
A
EGFR and ALK (gain of function mutation)
10
Q
ID
A
adenocarcinoma
11
Q
ID
A
adenocarcinoma (TTF-1 +)
12
Q
A
atypical adenomatous hyperplasia
13
Q
ID
A
adenocarcinoma in situ
14
Q
ID
A
adenocarcinoma
15
Q
most common mutations in small cell carcinoma
A
Loss of function TP53 and RB