Week 7: Lung Tumors and Molecular Testing Flashcards

1
Q

cancers highly associated with smoking

A

squamous and small cell carcinoma

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2
Q

most common transcription factor immunohistochemical stains in squamous cell carcinoma

A

p40 and p63

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3
Q

most common mutation in squamous cell carcinoma

A

CDKN2A and TP53

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4
Q

ID

A

Squamous Cell Carcinoma

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5
Q

ID

A

squamous metaplasia

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6
Q

ID

A

carcinoma in-situ high-grade dysplasia

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7
Q

ID

A

low-grade dysplasia

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8
Q

ID

A

Squamous Cell Carcinoma

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9
Q

most common mutations in adenocarcinoma

A

EGFR and ALK (gain of function mutation)

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10
Q

ID

A

adenocarcinoma

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11
Q

ID

A

adenocarcinoma (TTF-1 +)

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12
Q
A

atypical adenomatous hyperplasia

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13
Q

ID

A

adenocarcinoma in situ

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14
Q

ID

A

adenocarcinoma

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15
Q

most common mutations in small cell carcinoma

A

Loss of function TP53 and RB

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16
Q

ID

A

Small Cell Carcinoma

17
Q

ID

A

Small Cell Carcinoma

18
Q

ID

A

Small Cell Carcinoma

19
Q

ID

A

carcinoid tumor

20
Q

ID

A

atypical carcinoid

21
Q

ID

A

carcinoid tumor

22
Q

ID

A

atypical carcinoid tumor

23
Q

ID

A

solitary fibrous tumor

24
Q

ID

A

mesothelioma

25
Q

ID

A

asbestos exposure mesothelioma

26
Q

immunohistochemical stains in mesothelioma

A

calretinin and WT-1