Week 7 Lymph Part 4 Flashcards

1
Q

What is the center or inner portion of a lymph node called?

A

Medulla

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2
Q

What is the most superficial or outer layer of the node called?

A

cortex

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3
Q

Explain the layers of the lymph node? (superficial to deep)

A

Mature exterior, immature interior, superficial cortex, deep cortex, medulla

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4
Q

Lymphocytes are highly migratory or not?

A

VERY migratory

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5
Q

What are the two compartments of a lymph node?

A

Cortex and medulla

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6
Q

The cortex is comprised of a dense mass of lymphatic tissue such as?

A

Reticular framework, dendritic cells, lymphocytes, macrophages, plasma cells

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7
Q

Where do blood vessels enter and leave the lymph node?

A

Through the hilum INTO the medulla

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8
Q

The medulla consists of _____ of lymphatic tissue

A

Cords

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9
Q

The medulla consists of ‘cords’ of lymphatic tissue separated by?

A

Lymphatic sinuses or medullary sinuses

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10
Q

Lymphatic sinuses or medullary sinuses

A

Lymphocytes, macrophages, dendritic cells, and plasma cells

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11
Q

Cords in the lymph node are organized around _______ fibers?

A

Reticular, they are NOT physically attached -loosely surrounded

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12
Q

The medullary sinuses converge at the _____ and drain into _______ lymphatic vessels?

A

Converge at the HILUM and drain into the EFFERENT lymphatic vessels

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13
Q

Lymphatic vessels are lined by?

A

Cuboidal or columnar endothelial cells that allow for lymphocytes to move

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14
Q

What does aquaporin 1 do?

A

It is a water channel. Helps maintain volume of lymph fluid. Allows transfer of fluid into the bloodstream and causes lymph to enter through afferent vessels to be drawn deep into cortex

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15
Q

What is the thymus??

A

A bi-lobed organ located in the superior mediastinum, anterior to the heart and great vessels

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16
Q

Is the thymus more active in adults or children?

A

Children

17
Q

Explain the structure of the thymus?

A

It is surrounded by a thin capsule with trabeculae extending into the parenchyma

18
Q

The trabeculae create domains called?

A

Thymic lobules

19
Q

Each thymic lobule contains?

A

A cortex and medulla

20
Q

The capsule and trabeculae contain _________ and _____ lymph vessels?

A

Blood vessels and efferent lymph vessels

21
Q

Are there any afferent vessels in the thymus?

A

NO!

22
Q

Does lymph ‘flow’ though the thymus like it does lymph nodes?

A

NO!

23
Q

What is the thymus replaced with in an adult?

A

Adipose tissue

24
Q

What is the thymus function?

A

Lymphopoiesis during fetal and postnatal life

25
Q

What is lymphopoiesis?

A

The generation of, differentiation of lymphocytes

26
Q

Lymphopoiesis is more important in adults or children?

A

Children. (this is why it get filled with fat and is less important in adults)

27
Q

In adults, lymphocytes _____ in the thymus?

A

Proliferate

28
Q

Why do thymphocytes ONLY proliferate in the thymus?

A

Bc they develop in the bone marrow

29
Q

The thymic parenchyma contains developing T cells in a meshwork of ___________?

A

Epithelioreticular cells

30
Q

What are epithelioreticular cells?

A

These cells have features of epithelia and fibroblasts; forming the meshword to support T-cells

31
Q

Thymis or Hassall’s corpuscles are derived from?

A

Epithelioreticular cells

32
Q

What is the function of thymic or Hassall’s corpuscles?

A

Unknown