Female reproductive Flashcards
primordial follicle
- earliest stages of follicular devel
* single layer of squamous follicle cells with stretched out nucleus’s surround oocyte
balbiani body
localized accumulation of golgi bodies, ER, centrioles, mitochondria
primary follicle
- 1st growing stage of follicle
- CUBOID cells surrounding follicle
- zona pellucida - secreted pertinacious coat
follicle cells become?
granulosa cells after rapid replication as primary follicle
theca folliculi cells differentiate into two layers outside of granulosa cells
1) theca interna -highly vascularized cuboid STEROID producing secretory cells, fibroblasts and collagen
- -responds to LH by producing estrogen and androgen precursors
2) theca externa- outer layer of connective tissue; mainly smooth muscle cells and bundles of collagen fibers
boundary betwen theca interna and externa is?
indistinct; but the basal lamina and theca folliculi cells is distint
late primary follicle
- thick layer of granulosa cells, then basement membrane, then theca cells
- balbiani organelles disperse and multiply in cell
- have cortical granules
cortical granule
where sperm gains entry! closest to zone pellucida
oolema
oocyte plasma membrane
secondary follicles
*characterized by antrum
atrum
a bunch of hyaluronan (liquir folliculi) fluid filled spaces coalesce to form antrum
cumulus oophorus
thickened area of stratum granulosum in secondary follicles
corona radiate cells
cells incumulus oophorus that are in direct contact with oocyte and STAY IN CONTACT withreleased oocyte
cell-exner bodies
hyaluronan and proteoglycan aggregates between granulosa cells
mature or graafian follicles
spans entire thickness of ovarian cortex
*thecal layers more prominent