Week 7 Lymph Part 2 Flashcards
List supporting cells for lymphatic system
Monocytes, basophiles, dendritic cells (DC), Epithelioreticular cells, macrophages, eosinophils, follicular dendritic cells, neutrophils, reticular cells, langerhan’s cell (in skin)
What does CD stand for?
Cluster of differentiation
What do CD markers do?
Refer to different antigens present on different cell types at different stages of cellular differentiation, VERY good for IDing or diagnostic reasons
How do you ID lymphocytes?
By use of CD markers from the standardized international system to denote where they are in the differentiation process. They all look similar to the eye, big nucleus, blue, little cytoplasm BUT the cell surface is VERY different.
Why do CD markers work as identification?
Because some markers are only expressed throughout a cell’s lifespan and others are only present at specific phase of differentiation
Lymphatic vessels begin as a network of?
Blind capillaries in the loose connective tissue; blind= collect fluid and antigens
Describe lymphatic capillaries location?
More porous than blood capillaries, abundant in the papillary layer of dermis in the skin and in mucous membranes
The purpose of lymphatic capillaries is to?
Provide a collection point to drain and collect lymph from extracellular spaces
What is “lymph”?
Fluid, antigens, other ECM substances
As the lymph passes through the _____ ____ the lymphocytes have access to antigens
Lymph nodes
Lymphocytes circulate in both ____ and ______ vessels
Lymphatic and blood vessels
Lymph enters the lymph nodes via _____ lymphatic vessels?
Afferent
Lymphocytes in the blood enter the lymph node via?
Post capillary venules (high endothelial venules)
Lymphocytes T and B cells populate the same or different regions of the lymph node?
DIFFERENT
Lymphocytes and lymph leave the node via?
Efferent lymphatic vessels
