Week 5 Muscles 3 Flashcards

1
Q

How do you get release of Ca from sarcoplasmic reticulum?

A

Ryanodine receptors, on gated calcium realase channels

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2
Q

Transverse tubular system or T-system

A

Tubular invaginations of the plasma membrane that penetrate ALL levels of muscle fibers associated with the sarcoplasmic reticulum

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3
Q

sarcoplasmic reticulum is in close contact with?

A

Sarcolemma. * this is why the T-tubule system works*

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4
Q

Calcium activated ATPase pumps are where? Do what?

A

In the membrane of the sER andrestore calcium gradient

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5
Q

Ca realease = muscle _____

A

contraction

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6
Q

Ca uptake= muscle___

A

Relaxation, get ready for next contraction

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7
Q

What muscle type is voluntary?

A

skeletal

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8
Q

What muscle type is NOT striated?

A

Smooth

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9
Q

What muslce type IS striated?

A

Skeletal and cardiac

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10
Q

What muscle type is NOT voluntary?

A

Cardiac and smooth

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11
Q

What is the neuromuscular junction (motor end plate)?

A

Point at which the myelin sheath ends and the axon comes into contact with the muscle

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12
Q

What does an image of muscles with nerves look like?

A

a tree

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13
Q

Innervation is required to maintain muscle ____?

A

Integrity, either use it or lose it

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14
Q

Voltage centers are very close to? Does what?

A

Ryoidine receptors on the sER to TRIGGER Ca release.

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15
Q

The intimate relation between WHAT allows Ca to be released?

A

Sarcolemma, sER, and voltage centers on nerves

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16
Q

Cardiac muscle has a larger and better developed what compared to skeletal?

A

T-tubule system

17
Q

What are intercalated discs?

A

They are the cross bands/striations found in cardiac muscle. * special cell to cell contacts linking cardiomycytes together

18
Q

Main difference between skeletal and cardiac muscle?

A

1) Cardiac has single center nuclei
2) Cardiac has intercalated discs
3) Cardiac has a larger more developed T-tubule system

19
Q

Smooth muscle has different contraction initiation

A

1) mechanical impulse
2) Electrical depolarization
3) Chemical stimuli

20
Q

Smooth muscle does NOT have what system (but cardiac and skeletal do)?

A

T-tubule

21
Q

Afferent vs efferent nerve?

A

Afferent=sensory; efferent= motor

22
Q

Somatic vs autonomic nervous system?

A

Somatic=conscious and voluntary; autonomic= involuntary (smooth muscle, heart, glands)

23
Q

Neuroglia or glia cells?

A

Supporting cells near neurons

24
Q

Schwann cells

A

Surround the neuron processes and isolate them from adjacent cells and ECM

25
Q

Satellite cells have various purposes for nervous system

A

1) Support and protect neurons
2) Insulate nerve cell bodies
3) Repair neurons
4) Clearance for synapse

26
Q

Nerves have a lot of?

A

rER and free ribosomes, make a LOT of proteins

27
Q

Nissel bodies (will ID on exam)

A

Give neurons granuole appearance from staining of ribosome

28
Q

Three obvious structure to ID on neurons

A

1) Nissel bodies (aka ribosomes)
2) Nucleolus (nucleas is very light, nucleolus is dark)
3) Axon hillock

29
Q

Dendrite

A

Receive info, short, unmyelinated, CAN see organelles

30
Q

Axon

A

Convey info, only ONE, lacks large cytoplasmic organelles

31
Q

Axon hillock

A

Useful landmark, axons originate from the cell body here

32
Q

Difference in axodendritic, axosomatic, axoaxonic

A
  • Axodendritic= axon that terminate on dendrite
  • axosomatic= axon directly on cell body
  • axoaxonic= one axoncontacting another axon
33
Q

Difference in chemical synapses and electrical synapses

A
  • Chemical= conduction by release of chemicals (neurotransmeitters)
  • Electrical= in inverterbates, gap junction connections to allow passage of ions
34
Q

Presynaptic, synaptic cleft, and postsynaptic

A

Presynaptic is where an impulse is coming from (axon), passes the synaptic cleft, before transmitting on postsynaptic membrane (axon, dendrite or cell)