Week 7: Histology Flashcards

1
Q

ID the multicellular structure surrounding marker #1

A

Lymphoid Aggregate/MALT

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2
Q

ID the layer and major tissue type indicated by marker #2

A

Muscularis Externa/Propria and smooth muscle

the nuclei are corkscrew-shaped

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3
Q

ID the organ seen here

A

Appendix

No villi, short tubular glands, the entire structure fits on the slide, and lymphoid aggregates are present

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4
Q

Name the region of the organ

A

Jejunum

Absence of Brunner’s/Submucosal Glands and Peyer’s Patches

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5
Q

ID the layer and the tissue indicated by marker #1

A

Submucosa and DICT

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6
Q

ID the organ seen here

A

Colon

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7
Q

ID the epithelium indicated by marker #1

A

Simple Columnar Epithelium

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8
Q

ID the sublayer and tissue indicated by marker #2

A

Muscularis Mucosae and Smooth Muscle

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9
Q

What structure appears to be missing in this section and what physiological function would be disrupted in this patient?

A

Enteric Plexus and Peristalsis

both Meissner’s and Auerbach’s Plexus

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10
Q

What structure appears to be missing in this section and what embryonic cell type inappropriate migrated?

A

Enteric Plexus and Neural Crest

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11
Q

Name the region of the organ

A

Ileum

Peyer’s Patches are marker #2

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12
Q

ID the layer and tissue indicated by marker #1

A

Muscularis Externa/Propria and Smooth Muscle

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13
Q

ID the structure indicated by marker #2

A

Peyer’s Patch

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14
Q

ID the structure indicated by marker #3

A

Villus

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15
Q

ID the structures indicated by the arrows and what do they represent?

A

Terminal Bars; junctional complexes of epithelial cells

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16
Q

ID the structure indicated by the asterisks

A

Brush Border

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17
Q

Name the 3 most prominent enzymes located in the structure indicated by the asterisks

A
  • Enteropeptidase (Enterokinase)
  • Lactase
  • Aminopeptidase

asterisks are brush border

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18
Q

ID the structure indicated by the yellow ellipse

A

Taeniae Coli

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19
Q

Name the region of the organ seen here

A

Duodenum

Brunner/Submucosal Glands are markers #1 and #3

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20
Q

ID the structure indicated by markers #1 and #3

A

Brunner’s/Submucosal Glands

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21
Q

ID the function of the structures indicated by markers #1 and #3

A

Production of mucus to protect the mucosa layer of the duodenum

Marker #1 and #3 are Brunner’s/Submucosal Glands - they produce minimal bicarbonate

22
Q

ID the layer and sublayer in which markers #1 and #3 are located

A

Mucosa and Submucosa

23
Q

Name the structure that is located between markers #2 and #4

A

Plica Circularis (Circular Folds)

24
Q

Name two embryonic conditions through which this region might exhibit stenosis or atresia

A
  • Duodenal Atresia - incomplete recanalization during development
  • Annular Pancreas - failure of the ventral pancreatic bud to rotate

Both Show the double bubble sign on X-ray

25
ID the epithelium indicated by marker #1
Simple Columnar Epithelium
26
**ID the structure and tissue indicated by marker #2**
Villus and LCT ## Footnote The connective tissue core of the villus, which houses capillaries and lacteals is in the lamina propria, which is LCT
27
ID the structures indicated by markers 3 and 4
Intestinal Crypts or Crypts of Lieberkühn
28
What specific cell types are usually located in the structures indicated by markers #3 and #4
* Paneth cells * Goblet cells ## Footnote Marker #3 and #4 are Intestinal Crypts or Crypts of Lieberkühn
29
What normal feature of the mucosa of the duodenum is missing or severely blunted
Villi
30
Name the embryonic germ layer that the missing feature predominately derives from?
Endoderm ## Footnote Just the epithelium layer of the GI tract is endoderm; everything deep to the epithelium sublayer is mesoderm. i.e. lamina propria to serosa/adventia is mesoderm.
31
**ID the cells indicated by markers #1 and #2**
Paneth Cells
32
ID the function of the structures indicated by markers #1 and #2
Secrete lysozyme and alpha-defensin to protect against bacteria (innate immune system) ## Footnote Marker #1 and #2 are Paneth cells
33
Where are the structures indicated by markers #1 and #2 located?
Near the base of Intestinal Crypts or Crypts of Lieberkühn
34
What abnormality of the epithelium is the yellow arrow pointing to?
Intraepithelial Lymphocytes (IELs) ## Footnote T-cells in the case of Celiac Disease
35
If the reported histological slide was taken from the duodenum, what conditon would this patient be diagnosed with?
Celiac Disease
36
**Name the region of the organ**
Duodenum
37
ID the organ seen here
Colon
38
ID the cell indicated by marker #2
Goblet Cell ## Footnote Goblet Cells are Unicellular
39
ID the name and sublayer of the structure indicated by marker #3
Taeniae Coli and Muscularis Externa ## Footnote Taeniae Coli are just modifications to the outer longitudinal layer of the muscularis externa in the colon
40
ID structures #1 and #2, and what sublayer they are located in
Artery and Vein, respectively and Submucosa
41
ID structure #3
Myenteric/Auerbach's Plexus
42
ID structure #3
Submucosal/Meissner's Plexus
43
ID the predominant tissue located at marker #1
Skeletal Muscle
44
ID the predominant tissue located at marker #1 and its location
Cardiac Muscle and Ventricle
45
**Name the region of the organ that marker #1 is in its lumen**
Ileum
46
ID the structure whose lumen is indicated by marker #1
Hepatic Sinusoid
47
ID the cell whose nucleus is indicated by marker #2
Hepatocyte
48
ID the structure indicated by marker #1
Brunner's/Submucosal Gland
49
What is the function of the structure covering the luminal surface of the epithelium of marker #2?
Increased the surface area for more absorption
50
ID the organ seen here
Appendix ## Footnote Normally, can see the whole appendix in a slide. However, it is zoomed in a lot and you should use the presence of lymphoid aggregates, short glands, and lack of villi to identify it
51
ID the structure indicated by marker #2
Lymphoid Aggregate
52
ID the sublayer and tissue indicated by marker #3
Muscularis Mucosae and Smooth Muscle