Week 5: Small Intestines Flashcards
ID the layers and the two arrows
ID
Celiac Disease
Intraepithelial Lymphocytes (yellow arrows) and Villous blunting (cyan ellipse)
ID
Celiac Disease
Intraepithelial Lymphocytes (yellow arrows) and Villous blunting (cyan ellipse)
ID
Celiac Disease
Mucosal scalloping on endoscopy
What part of the small intestine does Celiac disease mostly affect?
Duodenum
What serological test do you use to help diagnose Celiac disease?
tissue TransGlutaminase testing (tTG-IgG)
What genetic mutation predisposes someone for Celiac disease?
HLA DQ2 and DQ8
If you have Celiac disease you can’t eat at Dairy Queen (DQ)
Parasitic infection where patients often present with diarrhea, smelly greasy poop that can float, fatigue, bloating and dehydration.
Giardias/Giardia
ID
Giardiasis/Giardia
“nail clipping” appearance on HE (yellow arrows)
Causative agent of Giardia/Giardiasis
Giardia lamblia
How do you acquire Giardia/Giardiasis?
Rivers and streams contaminated with fecal particles containing the eurkaryote
ID
Giardiasis/Giardia caused by Giardia lamblia
2 Trophozoites to 1 Cyst; Trophozoites have 2 nuclie that look like eyes, so this is the trophozoite
What part of the GI tract does Giardia primarily affect?
proximal small intestines, primarily the duodenum and sometimes jejunum
ID
Cryptosporidiosis
Protrusion balls (yellow arrows) are indicative of Cryptosporidiosis
What is the causative agent of Cryptosporidiosis
Cryptosporidium parvum
How do you acquire Cryptosporidiosis/Cryptosporidium?
Recreational water sources. i.e. public swimming pools
What part of the GI tract does Cryptosporidiosis/Cryptosporidium affect?
Terminal ileum
ID
Meckel’s Diverticulum
What is the “Rule of 2’s” for Meckel’s diverticulum
2% of population
~2 feet before the colon
~2 inches long
2 years of age or earlier for symptomatic occurences
Twisting of the bowels on itself
Like a ballon animal
Volvulus
What are the two most common locations of a Volvulus?
Ceacum and Sigmoid colon
ID
Volvulus
occurs when intestine slides into an adjacent part of the intestine. This telescoping action may cause obstruction. Most common in children
Intussusception
ID
Intussusception