Week 6: Cardiovascular Drugs Flashcards
What is the effect of aspirin?
Anti-platelet that reduces clot formation
What the side effects of aspirin?
- risk of gastric bleeding
- wheezing in some asthmatics
What are the contra-indications of aspirin?
- known allergy
- children under 16
- active GI bleeding
- haemophilia or clotting disorders
- severe hepatic failure with jaundice
What is the correct dosage of aspirin?
300 mg chewed or dissolved in water
What is the effect on entonox?
Inhaled analgesic gas
What are the side effects of entonox?
Minimal side effects
What are the contra-indications of entonox?
- chest injury
- suspected pnuemothorax
- decompression sickness diving <24hrs
- violently disturbed psychiatric patient
- abdominal pain where obstruction suspected
- intraoccular injection of gas in last 8 weeks
What is the dosage of entonox?
Self administered gas (3-5 mins effect)
What is the effects of GTN?
Dilation of coronary arteries, dilation os systemic veins resulting in <preload, reduced BP
What are the side effects of GTN?
- headaches
- dizziness
- hypotension
What are the contra- indications of GTN?
- hypotension’s
- hypovolaemia
- head trauma
- unconscious
- known severe aortic/mitral stenosis
- sildenafil/viagra in past 24hrs
What is the dosage of GTN?
400-800mgs (400mcg spray)
What is the effect of furosemide?
Potent diuretic with rapid onset and short duration
What are the side effects of furosemide?
- hypotensions
- GI disturbances
What are contra-indications of furosemide
- <GCS with liver cirrhosis
- cardiogenic shock
- severe renal failure with anuria
- children under 18
What is the dosage of furosemide ?
40mgs over 2 mins
What are the effects of paracetamol?
- analgesic
- antipyretic
What are the side effects of paracetamol?
- extremely rare
- may cause hypotension if admin too rapid
What are the contra indications of paracetamol?
- Known paracetamol allergy
What are the effects of morphine?
- strong opioid analgesic
- produces sedation/euphoria/analgesia
- histamine release
What are the side effects of morphine?
- resp depression
- cardio depression
- nausea/vomiting
- drowsiness
- pupil constriction
What are the contra-indications of morphine?
- children less than 1
- resp depression
- hypotension
- head injury with significant impaired LOC
- known hypersensitivity
