Week 5 - Muscular system Flashcards

Identify and explain the differences of the three types of muscle in the human body Describe the functions of skeletal muscle Identify and describe the anatomy of a skeletal muscle Explain the stages of the sliding filament theory Explain a what a motor unit is Explain the role of calcium and ATP in muscular contraction Explain the excitation-contraction coupling mechanism Acknowledge the differing fibre types

1
Q

Primary function of the muscular system

A

Produce movement in the body

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2
Q

Other functions of the muscular system

A
▪ Constriction of organs and vessels
▪ Cardiac contraction
▪ Respiration
▪ Postural maintenance
▪ Body heat production
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3
Q

3 types of muscle

A

Smooth muscle, cardiac muscle, skeletal muscle

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4
Q

2 striated muscle types

A

Skeletal and cardiac

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5
Q

2 involuntary muscle types

A

Cardiac and smooth

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6
Q

4 building blocks of muscle, largest to smallest

A

Muscle fascicle, muscle fiber, myofibril, myofilaments

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7
Q

What is a section of a myofibril called

A

sarcomere

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8
Q

3 layers of skeletal muscle connective tissue layers

A

Epimysium (surrounds muscle), perimysium (surrounds muscle fiber bundle), endomysium (surrounds muscle fiber)

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9
Q

Skeletal muscle organelles (6)

A

Sarcolemma, sarcoplasmic reticulum, transverse tubule, sarcoplasm, mitochondria, nucleus

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10
Q

Sarcolemma location and function

A

Location: On the cell membrane of muscle, fuses with tendon which fuses with bone

Function: Assists with action potentials along muscle, transports metabolites in and out of cell

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11
Q

Sarcoplasmic reticulum location and function

A

Location: Network of tubules run along and around myofibrils

Function: storage site for calcium

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12
Q

Transverse tubules location and function

A

Location: Extension of sarcolemma that pass laterally through cell

Function: Allow action potentials to be transmitted into the myofribrils

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13
Q

Names of fast and slow twitch muscle fibers

A

Slow - Type 1 (slow oxidative fibers) (SO)

Fast - Type 2a (fast oxidative glycolytic fibers) (FOG)

&

Type 2b (Fast glycolytic fibers) (FG)

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14
Q

What colour are Type 2a muscle fibers and why

A

White as they don’t need oxygen-rich blood to create fast energy

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15
Q

Sliding filament model/theory

A

Interaction of myofilaments cause muscle contraction and shortening

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16
Q

Myosin

A

Thick filaments are bundles of myosin molecules

17
Q

What does each globular head of myosin have

A

Myosin ATPase site and an Actin binding site

18
Q

Actin

A

Thin filaments are paried chains of actin molecules each with a myosin binding site

19
Q

Brown strands that wrap around Actin

A

Tropomyosin

20
Q

Troponin

A

Holds tropomyosin in place

21
Q

What prevents myosin from binding to the myosin binding sites on actin

A

Tropomyosin covers the binding sites and troponin holds tropomyosin in place

22
Q

What is the key to unlock troponin

23
Q

Where is calcium stores in the muscle

A

Sarcoplasmic reticulum

24
Q

Cross-bridge

A

Attachment of myosin to Actin

25
What is the energy molecule in the body?
Adenosine Triphosphate (ATP)
26
ATP turns into what when ATPase comes along
Adenosine Diphosphate (ADP) + Energy
27
Stages of sliding filament theory
1. Exposure of Active sites 2. Cross-Bridge formation 3. Power stroke 4. Cross-Bridge release 5. ATP to ADP and P 6. Recovery stroke Cross bridge cycling will occur again if Calcium is still connected to troponin
28
Without ATP what occurs and an example
Myosin and actin remain bound | In rigor mortis, the muscles stiffen because there is no ATP to release the bond
29
Functions that require ATP within the muscle
Power stroke Release of myosin from actin after power stroke Transporting calcium back to sarcoplasmic reticulum