Week 5 - Muscular system Flashcards

Identify and explain the differences of the three types of muscle in the human body Describe the functions of skeletal muscle Identify and describe the anatomy of a skeletal muscle Explain the stages of the sliding filament theory Explain a what a motor unit is Explain the role of calcium and ATP in muscular contraction Explain the excitation-contraction coupling mechanism Acknowledge the differing fibre types

1
Q

Primary function of the muscular system

A

Produce movement in the body

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2
Q

Other functions of the muscular system

A
▪ Constriction of organs and vessels
▪ Cardiac contraction
▪ Respiration
▪ Postural maintenance
▪ Body heat production
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3
Q

3 types of muscle

A

Smooth muscle, cardiac muscle, skeletal muscle

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4
Q

2 striated muscle types

A

Skeletal and cardiac

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5
Q

2 involuntary muscle types

A

Cardiac and smooth

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6
Q

4 building blocks of muscle, largest to smallest

A

Muscle fascicle, muscle fiber, myofibril, myofilaments

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7
Q

What is a section of a myofibril called

A

sarcomere

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8
Q

3 layers of skeletal muscle connective tissue layers

A

Epimysium (surrounds muscle), perimysium (surrounds muscle fiber bundle), endomysium (surrounds muscle fiber)

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9
Q

Skeletal muscle organelles (6)

A

Sarcolemma, sarcoplasmic reticulum, transverse tubule, sarcoplasm, mitochondria, nucleus

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10
Q

Sarcolemma location and function

A

Location: On the cell membrane of muscle, fuses with tendon which fuses with bone

Function: Assists with action potentials along muscle, transports metabolites in and out of cell

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11
Q

Sarcoplasmic reticulum location and function

A

Location: Network of tubules run along and around myofibrils

Function: storage site for calcium

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12
Q

Transverse tubules location and function

A

Location: Extension of sarcolemma that pass laterally through cell

Function: Allow action potentials to be transmitted into the myofribrils

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13
Q

Names of fast and slow twitch muscle fibers

A

Slow - Type 1 (slow oxidative fibers) (SO)

Fast - Type 2a (fast oxidative glycolytic fibers) (FOG)

&

Type 2b (Fast glycolytic fibers) (FG)

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14
Q

What colour are Type 2a muscle fibers and why

A

White as they don’t need oxygen-rich blood to create fast energy

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15
Q

Sliding filament model/theory

A

Interaction of myofilaments cause muscle contraction and shortening

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16
Q

Myosin

A

Thick filaments are bundles of myosin molecules

17
Q

What does each globular head of myosin have

A

Myosin ATPase site and an Actin binding site

18
Q

Actin

A

Thin filaments are paried chains of actin molecules each with a myosin binding site

19
Q

Brown strands that wrap around Actin

A

Tropomyosin

20
Q

Troponin

A

Holds tropomyosin in place

21
Q

What prevents myosin from binding to the myosin binding sites on actin

A

Tropomyosin covers the binding sites and troponin holds tropomyosin in place

22
Q

What is the key to unlock troponin

A

Calcium

23
Q

Where is calcium stores in the muscle

A

Sarcoplasmic reticulum

24
Q

Cross-bridge

A

Attachment of myosin to Actin

25
Q

What is the energy molecule in the body?

A

Adenosine Triphosphate (ATP)

26
Q

ATP turns into what when ATPase comes along

A

Adenosine Diphosphate (ADP) + Energy

27
Q

Stages of sliding filament theory

A
  1. Exposure of Active sites
  2. Cross-Bridge formation
  3. Power stroke
  4. Cross-Bridge release
  5. ATP to ADP and P
  6. Recovery stroke
    Cross bridge cycling will occur again if Calcium is still connected to troponin
28
Q

Without ATP what occurs and an example

A

Myosin and actin remain bound

In rigor mortis, the muscles stiffen because there is no ATP to release the bond

29
Q

Functions that require ATP within the muscle

A

Power stroke
Release of myosin from actin after power stroke
Transporting calcium back to sarcoplasmic reticulum