Week 3.2 The Bone Flashcards

1
Q

About 90% of the organic part of bone matrix is collagen; the rest includes

A

Proteoglycans and multiadhesive glycoproteins

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2
Q

In a developing long bone, the osteoblasts within the perichondrium form the

A

Bone Collar

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3
Q

During healing of a bone fracture, which tissues produce the woven bone that forms the callus?

A

Periosteum and endosteum

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4
Q

Parathyroid hormone causes

A

Stimulation of osteoclast activity.
Release of Ca ions from bone.
Resorption of bone matrix.

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5
Q

In a long bone, the primary ossification center is in the

A

Diaphysis

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6
Q

Which of these is true about bone?

A

Compact bone is a type of lamellar bone.
Cancellous bone is a type of lamellar bone
Lamellar bone is remodeled from woven bone.

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7
Q

Periosteum (both layers) contains

A

Type 1 collagen and fibroblasts
Blood vessels
Osteoblasts and osteoprogenitor cells.

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8
Q

The connective tissue that lines the bony trabeculae in the marrow cavity is called

A

Endosteum

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9
Q

In a bone fracture, which cells remove the blood cells of a hematoma?

A

Macrophages

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10
Q

What is the function of Sharpey fibers?

A

They bind the periosteum to the bone.

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11
Q

Cancellous bone is also known as

A

Trabecular bone

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12
Q

Hydroxyapatite is the mineral component of bone. It is composed primarily of which ions?

A

Calcium and phosphate

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13
Q

The result of epiphyseal closure is that

A

Growth in the length of the bone has stopped.

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14
Q

Secondary metastatic tumors in bone are the result of

A

Cancer cells from other organs that move into bones via small blood or lymphatic vessels.

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15
Q

How much of the dry weight of bone matrix is inorganic?

A

50%

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16
Q

Cells that reside in the lacunae in bone tissue

A

Osteocytes

17
Q

These cells secrete the newly deposited osteoid

A

Osteoblasts

18
Q

Secrete bone matrix

A

Osteoblasts

19
Q

A type of bone cells that is large and multinucleate

A

Osteoclasts

20
Q

These cells remodel bone tissue by breaking down the ossified matrix.

A

Osteoclasts

21
Q

Mesenchymal cells that give rise to osteoblasts

A

Osteoprogenitor cells

22
Q

Derived from monocyte blood cells

A

Osteoclasts

23
Q

These bone cells are connected by canaliculi

A

Osteocytes

24
Q

Cells that maintain the calcified matrix of bone.

A

Osteocytes