week 2-receptors

Question 1

All dopamine receptors are ____-____ ____ (or ____) receptors

Answer 1

g-protein coupled; metabotropic

Question 2

____ receptors are controlled by electrical statics, but largely rely on the size of ions.

Answer 2

Ionotropic

Question 3

____ receptors require chemical at binding site and changes conformation in order to start a cascade of events inside the cell

Answer 3

Metabotropic

Question 4

____ receptors are slower than ____ receptors since there are additional steps before signaling events

Answer 4

metabotropic; ionotropic

Question 5

____ receptors are located on an ion channel, but ____ receptors are not.

Answer 5

Ionotropic; metabotropic

Question 6

____ receptors can activate nearby channels and second messengers

Answer 6

metabotropic

Question 7

____ receptors increase the chance of action potential (major neurotransmitter: ____)

Answer 7

Excitatory; Glutamate

Question 8

____ receptors decrease the chance of action potential (major neurotransmitter: ____)

Answer 8

inhibitory; GABA

Question 9

____ receptors open a sodium channel, and ____ receptors open a calcium channel that requires 2 steps to open.

Answer 9

AMPA; NMDA

Question 10

What are the 2 required steps for NMDA receptor to open?

Answer 10

1. Glutamate bind to receptor
2. Membrane must be depolarized

Question 11

When ____ receptor is open, it allow Ca++ to flow into the cell, which triggers more ____ receptors to be deposited on the membrane, which ultimately leads to ____-____ ____.

Answer 11

NMDA; AMPA; Long-term potentiation

Question 12

____is a light gated sodium channel that can be used in ____.

Answer 12

channelrhodopsin; optogenetics