Week 2 Epithelial tissue histology Flashcards

1
Q

What ar4 basic tissue types?

A

Epithelial, connective, muscular, neural

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2
Q

Does epithelium have blood vessels?

A

No

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3
Q

Which surfaces of epithelial cells are specialised for communication?

A

Lateral and basal

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4
Q

What is the epithelium called on serosa?

A

Mesothelium

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5
Q

What does serosa line?

A

Body cavities and covers organs

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6
Q

Apcial surface modifcations of epithelial cells

A

Microvilli, cilia, stereocilia

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7
Q

Features of microvilli? Where found?

A

Actin filaments, + surface area. guts, kidney tubules. ABSORPTION

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8
Q

Features of Cilia? Where found?

A

Microtubules (doublets + dynein protein), move secretions, motile. airways, sperm.

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9
Q

Features of Sterocilia. Where found?

A

actin filaments, + surface area/ epididymus, inner ear

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10
Q

What is the core of cilia made from?

A

Axoneme (9+2 pattern of microtubule doublets)

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11
Q

What is at the terminal bar of epithelial cells?

A

Junctional complexes

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12
Q

What are the components of the Junctional Complex?

A

Zonula occludens, zonula adherens, macula adherens

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13
Q

Function of zonula occludens?

A

Tight junctions - draws neighboring cell membranes close. Adhesion & selective movement of ions and water thru intercellular space.

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14
Q

What filaments are linked in zonula occludens?

A

Actin filaments

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15
Q

Function of zonula adherens?

A

Lateral adhesion - Reinforces against mechanical stress. uniform 15nm between cells

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16
Q

Function of macula adherens?

A

Desmosome - strong attachment site between cells. Intercellular space = 30nm.

17
Q

What filaments connect to desmosomes?

A

Intermediate filaments

18
Q

What is lateral communication of cells mediated by?

A

Gap junctions - 6 proteins, circular channel

19
Q

T or F: Gap junctions are constantly open

A

False - open and close

20
Q

What is the function of the basement membrane?

A

Influences cell differentiation, regeneration, motility and shape. barrier,

21
Q

How do epithelial cells attach to basement membrane?

A

Hemidesmosomes