week 1: neurosci of memory/neurons Flashcards

1
Q

soma

A
  • cell body
  • contains nucleus and genetic info
  • directs protein synthesis
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2
Q

nucleus

A
  • contains genetic info
  • directs protein synthesis
  • supplies energy and resources the neuron needs to function
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3
Q

dendrites

A
  • part of neuron that extends away from cell body
  • main input to neuron
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4
Q

dendrite spine

A
  • protrusions on dendrite of neuron that form synapses w terminal buttons of presynaptic axon
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5
Q

axon

A
  • part of neuron that extends off soma and splits several times to connect w other neurons
  • main output of the neuron
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6
Q

action potential

A
  • transient all or nothing electrical current that is conducted down axon when membrane potential reaches threshold of excitation
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7
Q

synapses

A

junction between presynaptic terminal button of one neuron and dendrite, axon, soma of another postsynaptic neuron

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8
Q

resting electrical charge vs charge that is reached at action potential

A

-70mV, +40mV

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9
Q

myelin sheath

A
  • substance around neuron serve as insulation to allow action potential to conduct rapidly toward terminal buttons
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10
Q

gaps in the myelin sheath

A

nodes of ranvier

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11
Q

terminal button

A
  • part of the end of the axon that form synapses w post synaptic dendrite, axon, or soma
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12
Q

chemical substances released by presynaptic terminal button that act on postsynaptic cell are called _____ and when they form groups packaged together located near the terminal button theyre called ____

A

neurotransmitters, vesicles

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13
Q

excitatory neurotransmitters

A
  • ACh (Acetylcholine, enhanced effect improve/supressed decreases memory)
  • Glutamate (Glu, creating new memories)
  • Norepinephrine (memory colsolidation)
  • dopamine (memory processing)
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14
Q

inhibitory neurotransmitters

A
  • dopamine (memory processing)
  • Gamma-amino butyric acid (GABA, modification of glutamate, memory formation)
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15
Q

LTP

A
  • long term potentiation
  • strengthens connections between neurons by altering ease w which post synaptic neurons fire
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16
Q

LTD

A
  • long term depression
  • weakens connections between neurons
17
Q

four lobes and their function

A
  • frontal: action, emotion, thought, selecting and coordinating memory
  • parietal: sensory info/spacial processing
  • occipital: vision
  • temporal: visual and auditory processing, retaining info abt world
18
Q

which is arguably the most critical lobe for memory

A

temporal, includes hippocampus and medial temporal lobe

19
Q

default mode network

A
  • interconnected network of regions
  • more active when people are not engaged in an activity
20
Q

MRI

A
  • more accurate
  • used for brains but also joints, hearts, soft tissue
  • ## measures magnetic resonance
21
Q

CT

A
  • computer assisted tomography scan
  • can locate tumors, stoke damage, and brain condition
  • cheaper
21
Q

single cell recording/intracranial EEG

A
  • most direct way to measure brain activity
  • measures the electrical activity of action potential along axon
  • invasive
  • only in special populations
22
Q

EEG

A
  • less invasice but indirect
  • measures electrical activity over scalp
  • evenly spaced electrodes to localize origin activity
23
Q

MEG

A
  • uninvasive
  • larger sets of cells
  • Measures subtle changes in
    magnetic field over the scalp
    that are driven by underlying
    changes in electrical activity
24
PET
- invasive, injection with radioactive oxygen isotope - Travels through the blood to the brain, PET measures the level of isotope there
25
fMRI
- indirect - measures differences in levels of oxygenated blood
26
ERP
- event related potential - regular change in electrical activity as a function of particular task, condition or event
27
Event-Related (De)synchronization
- Synchrony of oscillations linked to memory
28
synaptic vs systems consolidation
- synaptic: formation of relatively enduring memories of recent experiences - systems: after synaptic consolidation, LTM gradually become independent from hippocampus