Week 1 Flashcards

1
Q

What is associated with von hippel lindau and where is the mutation

A

pheochromocytomas, retinal and cerebellar hemangioblastomas, and RCC. Mut is on chromosome 3 of VHL gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is indicative of a postictal state vs. syncope

A

confusion lasting for several minutes after a seizure. In syncope you return almost immediately to baseline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

after a carotid endarterectomy what is the more immediate risk and what is a risk in a couple months

A

immidiate - plaque embolism months- intimal hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

distinguish between early and late findings of alzheimers

A

early-forgetfullness, trouble driving places that were once commonplace, language difficulties, etc. LATE: urinary incontinence, dyspraxia, noncognitive deficits, urinary incontinence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

describe idiopathic intracranial HTN

A

typically an obese woman, likely because of outlet syndrome. You will see papilledema, negative imaging, elevated opening pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

normal pregnancy urine findings

A

trace protein is normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Sturge-Weber syndrome findings

A

port wine stain on the face into eye, risk of glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Phenytoin toxicity signs

A

cerebellar dysfunction, ataxia, altered mental status, hyperrflexia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How can an AV fistula in the arm for dialysis affect the median nerve

A

multifactorial, main thing to know is that it is carpal tunnel syndrome that is the main thing that happens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how do you manage traumatic brain injury

A

maintain central pressure, administer a antifibrinolytic (tranexamic acid), prevent seizures, control blood glucose, etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the likely etiology of a 20yo with new onset hearing loss with family hx of similar hearing loss at 20yo

A

NF2 bc of bilateral acoustic neuromas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the likely cause of a intracranial hemorrhage in a 40yo without any PMH

A

cocaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what do you give to a pregnant patient for migraine prophylaxis

A

a beta blocker, the other prophylaxis drugs are topiramate/valproate (toxic) or an antidepressant TCA or venlafaxine which also cannot be given

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Hallmarks of tuberous sclerosis

A

ash leaf spots, angiofibromas, and shagreen patches (papules in lumbosacral region), CNS tumors, autism, renal angiomyolipomas, cardiovascular rhabdomyomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

non pharmacological management of delirum

A

night sitter to reassure them that they are okay and tell them where they are at, helps get a full nights rest, avoid benzos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

symptoms of a parasagittal meningioma

A

bilateral leg weakness, urinary incontinence (frontal lobe dysfunction) and UMN signs in the lower limbs with preserved reflexes in the upper limbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

CSF in bacterial vs. fungal vs. viral meningitis

A

bacterial: low glucose high protein and PMNs // Fungal: low glucose, high protein but lymphocytes // viral: normal glucose, normal to high protein and lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is amaurosis fugax

A

this is transient occlusion of the retinal artery causing vision loss without pain. in an older individual it is often due to carotid emboli so a ultrasound of the neck should be done

19
Q

difference between adult vs. neonate meningitis presentation

A

adults: neck rigidity, fever, nausea/vomitting // infants: poor feeding, fever, jaundice, irritability, lethargy

20
Q

signs of DRESS syndrome and drugs that cause it

A

delayed reaction to mostly antiepileptics or antimicrobials // sx: facial edema, lymphadenopathy, eosinophilia, rash, fever // drugs: carbamazapine, phenytoin, lamotragine, dapsone, TMP/SMX, vanc

21
Q

signs and treatment of organophosphate poisoning

A

signs: DUMBELS // treatment: atropine (blocks the AChR itself) and then also pralidoxine

22
Q

what antibiotics do you give to neonates for meningitis

A

ampicillin, gentamicin, and cefotaxime

23
Q

which mutations mean early onset vs. late onset alzheimers

A

presenilin 1 for early and ApoE4 for late

24
Q

what is the main cause of death of acromegaly

A

congestive heart failure leading to reduced cardiac output

25
what is transient global amnesia
this is where you have sudden onset impairment of short term memory and ability to retain new information. no longer than 24 hours
26
signs of cocaine use
decreased appetite, weight loss, nervousness, conflict with family, dilated pupils, tachycardia, high BP, tremor, NORMAL refelxes
27
essential vs pill rolling tremor
essential: increases with a task, not seen at rest, gets better with alcohol // pill rolling: at rest, asymmetric, and parkinsons
28
how do you treat essential tremor
propanolol
29
what is the first line treatment for spinal mets from prostate cancer
high dose steroids to decrease inflammation and pain before surgery
30
describe cerebral amyloid angiopathy
this is when the beta amyloid plaques infiltrate into the brain and then they cause ICH in a lobar fashion. signs ans sx will be confusion and things related to the specific lobe
31
what are the signs of a lacunar stroke vs. larger ischemic strokes
lacunar: leg or arm weakness, NO focal signs, absence of cortical signs (aphasia, dysarthria, etc) NO mental status changes, often dont see them on imaging bc they are so small. Larger ones: focal signs, LOC etc.
32
signs of retinal detachment
curtain in front of vision, floaters, specific areas of vision loss, often in one eye not bilateral
33
describe the path of infection if a bug bites your face and say the signs and symptoms
travels from the facial vein or sinuses to the cavernous sinus causing a thrombosis // signs and sx: headache, periorbital edema, fever, vomiting etc .
34
first line diagnostics for a carotid bruit heard on physical exam
doppler ultrasound
35
first line diagnostics for an INFANT with full anterior fontanelles
ultrasound, dont want to CT bc of radiation exposure
36
signs of amantadine toxicity
livedo reticularis, orthostatic hypotension, peripheral edema, ataxia
37
how do you treat status epilipticus
IV benzo (lorazepam) --> phenytoin --> phenobarbital --> propofol
38
how do you diagnose ALS
electromyography
39
differentiate between peripheral and central facial nerve palsys
peripheral: forehead also affected // central: ipsilateral forehead is okay because of dual innervation peripherally
40
what are the signs of idiopathic intracranial hypertension
blurry vision, papilledema, diffuse headache,
41
differentiate between menieres and benign paroxysmal positional vertigo
Menieres: failure to absorb endolymph, tinitus, hearing loss // BPPV: crystals are displaced, do dix-halpike maneuver, vertigo
42
when should you not do a lumbar puncture?
if there are signs of increased intracranial pressure (such as confusion, somnolence, etc) bc of risk of herniation
43
what is the lesion type in prostate mets vs. multiple myeloma
prostate mets: sclerotic // multiple myeloma: lytic