W7- Haemophilus, & the HACEK Group Flashcards
HACEK group
-they all reside in human ORAL CAVITY and Nasopharynx and can cause Endocarditis
- Haemophilus
- Aggregabacterium
- Cardiobacterium
- Eikenella
- Kingella
General characteristic of HAEMOPHILUS
- gram (-)
- PLEOMORPHIC coccobacilli or rods
- facultative anaerobic
- ferment carbohydrates
- obligate parasite
- “blood lover’
- require performed growth factors present in blood
Haemophilus
What is the major pathogenic species in the genus Haemophilus
- H. influenzae
- H. aegyptius
- h. ducreyi
X factor
-hemin or hematin
X for UNKNOWN
V factor
- nicotinamide adenine dinucleotide NAD
- V for VITAMIN
T/F
Haemophilus spp. with the prefix PARA need only V factor for growth
TRUE
T/F
if they are V factor dependent they DO NOT GROW in SBA
TRUE
A phenomenon that helps in the recognition of Haemophilus spp. that need V factor
SATELLITISM
T/F
Satellitism happens when an organism, such as S. aureus, S. pneumoniae, Neisseria spp., produces V factor as a by-product of metabolism -
TRUE
What is the virulence factor of Haemophilus influenzae
- capsule
- IgA protease
- Adherance by fimbriae & other structures
- outer membrane proteins & LPS
What virulence factor plays the most signif8icant role (not a;; strains) of H. influenzae
CAPSULE
What serotype of H. influenzae caused the most invasive infection leading cause of meningitis
SEROTYPE B
T/F
NOT ALL strains of H. influenzae are encapsulated
TRUE
What species of the Genus Haemophilus produces IgA protease
H. influenza
