1- GRAM POSITIVE SPORE-FORMING BACILLI CATALASE POSITIVE Flashcards
-causative agent of anthrax
- largest pathogenic bacteria
-are capable of forming
Bacillus
MOT for bacillus
-inoculation
-injection
-ingestion
-inhalation
inhibits phagocytosis; not polysaccharide capsule
Poly-glutamyl capsule
impairs neutrophil function, and causes massive edema
Edema factor (EF)
promotes entry of EF intro phagocytic cells
Protective antigen
stimulates the production of TNF and IL-1
Lethal Factor
four forms of disease
- cutaneous anthrax
- gastrointestinal anthrax
- inhalational anthrax
- injectional anthrax
presumptive test for bacillus anthrax
immunochromatographic test
Susceptibility test
string of pearl
serotest to detect/ diagnose anthrax
Ascoli test
-also known as Fried Rice bacillus
- found within the soil and widely distributed in
-opportunistic pathogen and often associated with food borne illness
Bacillus cereus
two types of symptoms caused by bacillus cereus
Diarrheal, emetic
box car morphology/ bamboo fishing rod
Bacillus anthracis
-most common biological indicator
- hay bacillus
-ground glass appearance
Bacillus subtilis
biological indicator of autoclave/ moist heat
Bacillus stearothermophilus
causes Spastic paralysis
C. tetani
causes Flaccid paralysis
C. botilinum
clostridium welchii/ gas gangrene bacillus
C. perfringens
virulence factor for Ctetani
tetanospasmin
-blocks the release of neurotransmitters causing spastic paralysis
cardinal signs of tetanus
trismus / lock jaw
risus sardonicus/ devil’s grin
opisthotonus/ arching of the back
gram staining $ microscopy of C. tetani
Gram neg with terminal spore tennis racket/ drum stick or lollipop appearance
colonoy morphology of C. perfringens on 5%BAP
double zone or hemolysis/ target hemolysis
positive for lecithinase
C. perfringens
positive for lipase
C. botilinum
