W23-L1: Cellular Basis of Epilepsy Flashcards
What is the most common serious chronic neurological condition?
Epilepsy
What is an epileptic seizure?
A transient occurrence of clinical signs and/or symptoms due to excessive and hyper-synchronous activity of populations of neurons in the brain
What is epilepsy?
A group of neurological diseases with enduring alterations in the brain resulting in abnormally increased predisposition to seizures
What are the causes of epilepsy?
Genetic, structural/metabolic and unknown
What are the three main classes of seizures?
- Partial seizures
- Generalised seizures
- Unclassifiable seizures
What is a partial seizure?
Arise in a limited number of cortical neurones within one
hemisphere
What is the most common cause of a partial seizure?
Structural or metabolic abnormalities
What are generalised seizures?
Appear to arise simultaneously in both hemispheres.
What is the most common cause of generalised seizures?
Genetic
Why is classifying epilepsies important?
- Prognosis
- Treatment options
- Genetic implications
What causes epilepsy?
Disturbance in the balance between inhibition and excitation of cortical neurones and neuronal networks.
T/F Having a seizure promotes the chance of having another seizure?
True
When are the age peaks of epilepsy seen?
Young and Old
What is the most common pathology in adults with partial epilepsy?
Mesial Temporal Sclerosis
