Vitamins and Minerals Flashcards

1
Q

vitamins cannot be synthesized by the body, the two exceptions are

A

niacin and vitamin D

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2
Q

fat soluble vitamins

A

ADEK

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3
Q

hematopoietic vitamins

A

folic acid and B12

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4
Q

fat soluble vitamin that is an important antioxidant

A

vitamin E

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5
Q

fat soluble vitamin that is important for vision

A

vitamin A

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6
Q

vitamin required for clotting factors II, VII, IX and X

A

vitamin K

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7
Q

fat soluble vitamins are stored where

A

liver

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8
Q

fat soluble vitamin stored in the least amount, therefore manifests first as a result of absorptive deficiency

A

vitamin K

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9
Q

primary vitamin deficiency is related to

A

diet

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10
Q

name of vitamin A form required for dim light vision

A

11-cis retinal

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11
Q

name of vitamin A form required for epithelial growth

A

retinoic acid

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12
Q

pro vitamin form of vitamin A

A

beta carotene

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13
Q

name of vitamin A form required for maintenance of reproductive tissues

A

retinol

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14
Q

11-cis retinal goes into the rod cell and combines with _____ to form _______

A

opsin, rhodopsin

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15
Q

dim light converts rhodopsin into opsin and

A

all trans retinal

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16
Q

symptoms of vitamin A deficiency

A

night blindness, xerophthalmia, bitot spots, keratomalacia

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17
Q

raised intercranial pressure that mimics brain tumor with dry, peeling skin

A

hypervitaminosis A

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18
Q

precursor for vitamin D synthesis

A

7 dehydrocholesterol

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19
Q

name of inactive vitamin D

A

cholecalciferol

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20
Q

name of active vitamin D

A

1,25 dihydroxycholecalciferol

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21
Q

where is vitamin D activated

A

in the kidney

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22
Q

rate limiting enzyme for activation of vitamin D

A

1-hydroxylase

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23
Q

organ that vitamin D works on

A

intestine to increase calcium absorption, bone to promote mobilization of calcium & kidney to inhibit calcium excretion

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24
Q

bow legs, pigeon chest, frontal bossing, increase alkaline phosphatase

A

rickets ( vitamin D deficiency )

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25
old person, fragile bones, high alkaline phosphatase, renal failure
osteomalacia
26
active form of vitamin E
alpha tocopherol
27
vitamin E deficiency can manifest as
hemolytic anemia or loss of deep tendon reflexes
28
administration of broad spectrum antibiotics is a risk factor for what vitamin
K
29
gamma carboxylation allow for ______ binding
calcium
30
intercranial bleeding in newborn is due to which vitamin deficiency
vitamin K
31
drug that is a vitamin K antagonist
warfarin
32
hematuria, melena, bleeding gums, mad bruises
vitamin K deficiency
33
vitamin required for collagen synthesis
vitamin C
34
collagen enzymes that need vitamin C
proline hydroxylase and lysine hydroxylase
35
bleeding gums, loose teeth, mad bruises, perifollicular hemorrhages
scurvy
36
type of reactions that require B1
oxidative decarboxylation
37
Vitamin A can be used to treat
acne, and psoriasis
38
difference between wet and dry beri beri
wet deal with cardiovascular and dry is neural
39
syndrome associated with chronic alcoholics and thiamine deficiency
wernike-korsakoff
40
name of vitamin B2 and where its used
riboflavin, Stuff that need FAD or FMN (complex II of ETC)
41
Symptoms of riboflavin deficiency
cheliosis, glossitis, and dermatitis
42
name for vitamin B3 deficiency
pellagra
43
For d's of pellagra
Dermatitis, dementia, diarrhea, death
44
Pellagra is associated with which disorder
Hartnups
45
Amino acid that can synthesize niacin
Tryptophan
46
3 reactions that require biotin
Pyruvate carboxylase, acetyl CoA carboxylase, Propionyl CoA carboxylase
47
Enzyme in eggs that inhibits absorption of biotin
avidin
48
vitamin used in decarboxylation reactions
B6
49
drug that inhibits PLP
isoniazid
50
isoniazid is used to treat
Tuberculosis
51
Type of anemia seen in vitamins B6 deficiency
Microcytic anemia
52
Absorption of B12 is done by
Intrinsic factor
53
Type of anemia seen in patients without intrinsic factor
Pernicious anemia
54
Eukaryotic drug that is a folic acid antagonist
Methotrexate
55
Mineral required for synthesis of cross-links in collagen
Copper
56
collagen enzyme that requires copper as a cofactor
lysyl oxidase
57
copper defect where hair is gray, twisted and kinky (old Nigerian hair)
menkes syndrome
58
Accumulation of copper in the brain, liver and eye
wilsons disease
59
keyword for wilsons disease
Kayser- Fleischer rings
60
genetic defect causing excessing absorption of Iron
hereditary hemochromatosis (iron stored in liver and pancreas)