Integrative metabolism: Adipose, Muscle & Brain Flashcards

1
Q

percentage of TAG in adipocytes

A

60%

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2
Q

percentage of energy storage in adipose tissue

A

83%

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3
Q

major enzyme for lipolysis

A

hormone sensitive lipase

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4
Q

major enzyme for lipogenesis

A

lipoprotein lipase

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5
Q

In adipocyte glycerol 3-P is obtained from glycolysis via

A

DHAP

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6
Q

stimulates Glut 4 transporters on adipocytes

A

insulin

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7
Q

stimulates synthesis of LPL on adipocytes

A

insulin

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8
Q

Apo protein that stimulates LPL

A

Apo C-II

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9
Q

hormone that leads to HS lipase activation

A

epinephrine

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10
Q

glycerol kinase is found

A

in liver only

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11
Q

ETC uncoupler found in brown adipose

A

thermogenin

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12
Q

hormone that mediates appetite suppression

A

leptin

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13
Q

leptin receptors are found where

A

hypothalamus

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14
Q

hormone that function in regulation of AMPK

A

leptin

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15
Q

leptin induces expression of

A

UCP-2

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16
Q

anabolic pathways remain active when AMPK is activated by

A

leptin, opposed to AMP which shuts off all anabolic pathways

17
Q

type IIB muscle fibers

A

fast glycolytic

18
Q

type IIA muscle fibers

A

fast oxidative

19
Q

type I muscle fibers

A

slow twitch

20
Q

muscle fiber with most glycogen storage

A

type IIB

21
Q

color of type IIB fibers

A

white

22
Q

muscle fiber with highest oxidative capacity

A

type I

23
Q

acts as storage of high energy phosphate bonds

A

creatine phosphate

24
Q

percentage of oxygen consumption by muscle at rest

A

30%

25
Q

percentage of oxygen consumption by muscle during exercise

A

90%