Integrative metabolism: Adipose, Muscle & Brain Flashcards
percentage of TAG in adipocytes
60%
percentage of energy storage in adipose tissue
83%
major enzyme for lipolysis
hormone sensitive lipase
major enzyme for lipogenesis
lipoprotein lipase
In adipocyte glycerol 3-P is obtained from glycolysis via
DHAP
stimulates Glut 4 transporters on adipocytes
insulin
stimulates synthesis of LPL on adipocytes
insulin
Apo protein that stimulates LPL
Apo C-II
hormone that leads to HS lipase activation
epinephrine
glycerol kinase is found
in liver only
ETC uncoupler found in brown adipose
thermogenin
hormone that mediates appetite suppression
leptin
leptin receptors are found where
hypothalamus
hormone that function in regulation of AMPK
leptin
leptin induces expression of
UCP-2
anabolic pathways remain active when AMPK is activated by
leptin, opposed to AMP which shuts off all anabolic pathways
type IIB muscle fibers
fast glycolytic
type IIA muscle fibers
fast oxidative
type I muscle fibers
slow twitch
muscle fiber with most glycogen storage
type IIB
color of type IIB fibers
white
muscle fiber with highest oxidative capacity
type I
acts as storage of high energy phosphate bonds
creatine phosphate
percentage of oxygen consumption by muscle at rest
30%
percentage of oxygen consumption by muscle during exercise
90%
