Diabetes Mellitus Flashcards
to be considered diabetic, the fasting blood glucose levels need to be higher that
126
non-insulin dependent diabetes
type 2
type of diabetes that has the highest percentage of victims
type 2 (90%)
diabetes during pregnancy that normalizes after delivery
gestational
type ___ diabetes is characterized by autoimmune destruction of ____ cells of the pancreas
1, beta
insulin resistance has been defined as the requirement of _____ or more units of insulin per day
200
incretin that increases insulin secretion
GLP-1
classical triad of presenting features of diabetes
polydipsia, polyphagia, polyuria. (thirst, hunger, pee)
results in an insulin independent uptake of glucose by skeletal muscle
exercise
acute complication of type 1 diabetic
ketoacidosis
acute complication of type 2 diabetic
hyperosmolar non-ketoic coma
type of diabetes in a patient with hyperglycemia, weight loss and increased ketone bodies
type 1
type of diabetes in a patient with hyperglycemia, normal ketone bodies
type 2
why is ketosis not present in type 2 diabetics
they still are able to produce a small amount of insulin that will inhibit lipolysis
microvascular complications of diabetes
neuropathy, nephropathy, and retinopathy
hyperglycemia results in ______ formation that causes tissue damage and ______ of _______ that contibutes ot nephropathy
sorbitol, glycation, proteins
complications in chronic diabetics
micro and macro vascular
earliest indicator of renal involvment in diabetic
increased loss of albumin in the urine. (microalbuminuria)
macrovascular complications are usually due to decreased action of
lipoprotein lipase, which is stimulated by insulin
indicator of longterm glucose levels
HbA1c
elevated HbA1c is levels greater than
6.5%
test used to evaluated the ability to regulate glucose metabolism
OGTT
patient with normal fasting glucose but post prandial glucose is more than 140
impaired glucose tolerance
drug that increases insulin secretion from pancreas
sulfonylurea
Drug that decreases glucose output by liver
metformin