Viruses Flashcards

1
Q

List the 5 virus factors

A

Life cycle
Tropism
Invasiveness
Opportunism
Virulence

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2
Q

What are the host factors?

A

Age
Genetic
Immune
Trauma

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3
Q

List the sources of viruses

A

Social
Food
Environment
Occupation
Sexual
Travel

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4
Q

How do we get exposed to viruses?

A

Orally
Respiratory
Percutaneously

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5
Q

What are the characteristics of viruses that we use to classify them?

A

Type of nuclei acid: DNA or RNA
Single or double strand

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6
Q

What is the distinguishing feature of a virus?

A

Obligate intracellular parasites

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7
Q

What proteins to viruses encode for?

A

Structural and functional proteins for self perpetuation

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8
Q

What cellular components are required for viral propagation?

A

Translation of viral mRNA
Enzymes for replication
Transport pathways
Energy source

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9
Q

What does the basic virus structure look like?

A

Envelope
Surface proteins
Capsid
Viral genome
Enzymes

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10
Q

What are the essential components for a virus to have?

A

DNA/RNA genome
Capsid core
Polymerase protein

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11
Q

What is the protein subunit of a capsid?

A

Capsomere

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12
Q

What is the viral genome enclosed by?

A

Nucleocapsid

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13
Q

What are the three types of symmetry in a virus?

A

Icohedral
Helical
Complex

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14
Q

How does a virus obtains an envelope?

A

From lipid bilayer of host cell membrane

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15
Q

What does a viral envelope determine?

A

Stability of virions outside the host
Mode of transmission

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16
Q

What viruses are able to be transmitted by food/water?

A

Non enveloped - stable

17
Q

What is the importance of viral surface proteins?

A

Attach to membrane proteins in host cell
Determine tropism
Target for antibodies

18
Q

How do viruses replicate?

A

Attaches to host cell
Passes in through endocytosis
Nucleic acid is uncoated
Viral RNA enters nucleus and is replicated
Release

19
Q

What is the main concern for the outcome of hepatitis B virus?

A

Risk of chronic hepatitis
Cirrhosis
Hepatocellular carcinoma

20
Q

What are four examples of RNA viruses?

A

Polio
Influenza
Mumps/measles
HIV

21
Q

How do we diagnose viral infections?

A

Nucleic acid detection
Antigen detection

22
Q

What is a superficial viral infection?

A

Acute infection in epithelium
Short duration 2-4 days
Cold, influenza

23
Q

What do we call an infection where the virus replicates at multiple sites?

A

Systemic infection

24
Q

What is the difference between a persistent and latent infection?

A

Persistent - continue to produce infectious virus, evade immune system, continue to produce virus
Latent - virally persistent but asymptomatic and do not replicate to produce new viruses