Infectious Diseases Flashcards

1
Q

What is infection?

A

Tissue invasion by microorganisms causing disease

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2
Q

How are infections classified?

A

Community acquired
Health-care associated

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3
Q

What are important factors in the medical history?

A

Foreign travel
Occupation
Pets
Sex
Drugs
Injections
HIV

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4
Q

What are the baseline investigations for an infection?

A

liver function tests
Urinalysis
Chest X ray

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5
Q

What are the most common viral infections?

A

Herpes
HIV

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6
Q

What is the difference between type 1 and type 2 herpes?

A

Type 1: transmitted through saliva
Type 2: transmitted through sex

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7
Q

What is the clinical significance of herpes?

A

Causes severe ulcers around the mouth, genitals, eyes
Mortality rate 80% if baby catches

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8
Q

What is herpes zoster and how does it present?

A

Viral infection
Reactivation of varicella-zoster virus
Painful self limited rash

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9
Q

What are the complications of herpes zoster?

A

Post hermetic neuralgia
Will feel itchy and area is sensitive
Hyperalgesia

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10
Q

How do we treat herpes zoster?

A

Acyclovir

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11
Q

What is the limitation of treatment of herpes zoster?

A

No effect on post hermetic neuralgia

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12
Q

What is the virus that causes infectious mononucleosis?

A

Epstein-Barr virus

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13
Q

What are the clinical features of mononucleosis?

A

Anorexia
Malaise
Fever
Sore throat
Cervical lymphadenopathy
Macular Rash
Tonsillitis

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14
Q

What are the long term complications of infectious mononucleosis?

A

Hepatitis
Respiratory obstruction
Ruptured spleen

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15
Q

How do we diagnose mononucleosis?

A

Mono spot test

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16
Q

What virus causes chickenpox?

A

Varicella zoster virus

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17
Q

What are the complications of chicken pox?

A

Pneumonia
Neurological
Cellulitis

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18
Q

How do we treat chicken pox?

A

Antihistamines
Acyclovir

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19
Q

What virus causes mumps?

A

Paramyxovirus

20
Q

How is mumps spread?

A

Droplet infection

21
Q

What are the clinical features of mumps?

A

60% symptomatic
Fever
Malaise
Enlargement of parotid gland
Earache
Swallowing and submandibular glands affected

22
Q

What are the complications of mumps?

A

Neurological
Meningitis
Affects: ovaries, thyroid, pancreas and breasts

23
Q

How do we treat mumps?

A

Good OH
Scrotal support
Bed rest

24
Q

What are the childhood exanthems for mumps?

A

Measles
German measles
Mononucleosis
Scarlet fever
Erythema

25
Q

What is the virus that causes measles?

A

Paramyxovirus

26
Q

What are the clinical features of measles?

A

Conjunctivitis
Lymphadenopathy
Kopliks spots on buccal mucosa
Rash

27
Q

What are the complications of measles?

A

Gingivostomatitis

28
Q

What is German measles caused by?

A

Rubella

29
Q

What is the difference between measles and German measles?

A

German measles doesn’t cause gingivostomatitis
Can cause build up of mucus in airway

30
Q

What causes enteroviral infections?

A

Coxsackie virus a and b

31
Q

What is an example of enteroviral infection?

A

Hand foot and mouth disease

32
Q

What are the clinical features of enteroviral infections?

A

Fever
Malaise
Anorexia
Sore throat
Vesicular rash
Hands 65%

33
Q

What is parvovirus B19?

A

Erythema infectiosum
Slapped cheeks

34
Q

How are hepatitis B and C spread?

A

Infected blood
HBV in saliva

35
Q

What are the clinical features of HCV?

A

Lichenoid reaction
Xerostomia

36
Q

Wha type of infection is scarlet fever?

A

Bacteria

37
Q

What is scarlet fever caused by?

A

Beta haemolytic streptococci

38
Q

What are the clinical features of scarlet fever?

A

Pharyngeal infection
Rash that blanches on pressure
Strawberry tongue

39
Q

What is the incubation phase of whooping cough?

A

7 days
Build up of mucus 1-2 weeks

40
Q

What gram negative bacilli causes whooping cough?

A

Bordetella pertussis

41
Q

What are the clinical features of whooping cough?

A

4-6 weeks inspiratory whoop cough
Vomiting
Laceration of lingual fraenum

42
Q

How do we test for whooping cough?

A

Para nasal swabs
Immunofluorescent antibody test

43
Q

Is TB viral or bacterial?

A

Bacterial
Rising in the UK

44
Q

What is the cause of TB?

A

Myobacterium tuberculosis

45
Q

Which vaccine immunises against TB?

A

BCG

46
Q

What is seen in the mouth of TB?

A

Swelling of gums and lips

47
Q

What is a relevant fungal infection?

A

Oral candidiasis