Virus Part 2.1 ( Prions & Protein Infectious )

Question 1

What does prions stand for?

Answer 1

PROteinaceois
INfectious
Particles

Question 2

Are prions viruses?

Answer 2

No

Question 3

Are prions bacteria?

Answer 3

No

Question 4

What are diseases associated with prions ? (3)

Answer 4

Kuru
Mad cow
Creuztfeld Jacob disease

Question 5

What are prions? Cells? No cells?

Answer 5

They are literally just infectious proteins floating around

Question 6

Are prions the most resistant in trying to kill?

Answer 6

Yes

Question 7

Are prions fatal? And are they slow infection?

Answer 7

Yes

Question 8

What does prion disease causes? Or more so how does it effect us? And appearance of what ?

Answer 8

All are neurological disease
Spongy appearance of the brain

Question 9

What is the prototype of prions?

Answer 9

Mad cow disease

Question 10

What is PrPc ?

Answer 10

Normal cellular protein

Question 11

What is PrPsc?

Answer 11

Scrapie protein, accumulates in brains cells, forming plaques

Question 12

How does prions infect us? (2)

Answer 12

Goes to the brain
Converts normal protein into infectious abnormal protein

Question 13

How can prions spread? (3)

Answer 13

Comminated tissues
( cow eats sheep tissues )
Genetically inherited
Dirty equipment

Question 14

Why is it called PrPsc ( scrapie )?

Answer 14

Because when we feed the cow the sheep’s tissues, the sheep was suffering from a disease of scrapie

Question 15

What are the 8 steps for prions infections?

Answer 15

1. The normal PrPc is on surface
2. PrPsc is acquired or genetically mutated
3. PrPc reacts PrPsc on surface
4. PrPsc converts PrPc into PrPsc
5. Keeps converting
6. PrPsc enters through endocytosis
7. PrPsc accumulates in endosomes
8. Endosomes turn into lysosomes ( kills the cell )

Question 16

Is there a cure, vaccine, treatment for cow disease?

Answer 16

No

Question 17

What is Kuru?

Answer 17

Cannibalism
( Eating dead people, brain and heart )

Question 18

Prions are heat resistant ?

Answer 18

Yes, very, prions will survive it

Question 19

A provirus can be removed from a host cells? ( true or false )

Answer 19

False

Question 20

What are viroids? And causes?

Answer 20

Small pieces of naked rna that dause plant disease

Question 21

Viroids are closed and _____?

Answer 21

folded, that protects it from cellular enzymes

Question 22

Does viroids rna code for anything?

Answer 22

Nope