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Microbiology Exam 3 > Nonspefic Innate Immune Part 2 > Flashcards

Nonspefic Innate Immune Part 2 Flashcards

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1
Q

Do we produce natural anti microbial substances ?

A

Yes

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2
Q

What are the 2 anti microbial substances ?

A

Interferons
Complement

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3
Q

What does interferons kill ?

A

Kill viruses
( antiviral )

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4
Q

What does complement kill ?

A

Kill bacteria & viruses
( anti bacterial & anti viral )

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5
Q

What are interferons?

A

Small proteins produced by some animals cells after viral infection

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6
Q

How does IFN act ?

A

By stimulating cells to produce antiviral proteins ( AVPS ) to stop viral replication

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7
Q

What does AVP stand for?

A

Anti viral proteins

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8
Q

What are the 3 types of IFNs?

A

Alpha- interferon
Beta- interferon
Gamma- interferon

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9
Q

Interferons are viral specific?

A

No

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10
Q

Are interferons host specific?

A

Yes

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11
Q

What is considered the first line of defense against viral infections?

A

Interferons

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12
Q

Can every cell produce all 3 types of interferons? However are specific cell types produce specific interferons?

A

Yes, all cell can make all 3

And yes, certain cells make certain interferons

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13
Q

What does alpha interferon produce?

A

B lymphocytes and monocytes

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14
Q

What does beta interferon produce?

A

Fibroblasts & epithelia cells

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15
Q

What does gamma interferons produces?

A

T cells

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16
Q

What is complement system?

A

Individual proteins are inactive in the blood until activated by the presence of a foreign cell (bacteria or virus ) in the body

17
Q

How many complement proteins are found in ???

A

30 proteins found in serum

18
Q

What is serum?

A

Fluid portion of the blood

19
Q

Are complements only apart of innate system?

A

Yes

20
Q

What are the 3 ways complement destroys microbes?

A

Cytolysis
Inflammation
Phagocytosis

21
Q

Why is it nonspecific mechanism?

A

For removing foreign cells

22
Q

What is a cascade?

A

The first protein activated which then activated others proteins

23
Q

What are the 3 pathways for complement system?

A

Classical
Alternative
Lectin

24
Q

What does c3b do in the complement system?

A

Opsion

25
Q

What is an opsoin?

A

Promotes phagocytosis

26
Q

What are 2 major opsoins?

A

C3B & anti body molecule

27
Q

Is c3b a protein?

A

Yes

28
Q

What difference between complement and interferon?

A

Complement - anything
Interferon - viruses

29
Q

Is fever apart of inflammation?

A

NO!!!

30
Q

Once c3B gets activate what is enhanced?

A

Cytolysis
Inflammation
Phagocytosis

31
Q

Is opsonization the process of enhancing inflammation?why?

A

No!!

( because it’s a part of phagocytosis )

Microbiology Exam 3 (12 decks)

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