Virus Intro & Positive Strand RNA Flashcards

Dr. Schein

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1
Q

Dengue can cause _____ fever sometimes and Shock Syndrome

A

Hemorrhagic

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2
Q

Jap/ Saint Louis Encephalitis, West nile, Dengue, Yellow Fever, and Zika are all examples of _____virus

A

Flavi

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3
Q

The togavirus, Alphavirus uses humans as an ______ host

A

Accidental

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4
Q

Zika virus is classified as a _____virus

A

Flavi

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5
Q

DNA viruses tend to stay in the _____, except for POX

A

Nucleus

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6
Q

Among the Flaviviruses, what do Japanese, Saint Louis, and West Nile all share in common?

A

Accidental human hosts

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7
Q

Coxsackie, Echo, and Poliovirus are all subclasses of the _____-virus which are all Picornaviridae

A

Entero

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8
Q

____ fever goes monkey to monkey via Haemogogus and humans are accidental host; It’s a Flavi virus

A

Yellow

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9
Q

2 Features common to Flaviviridae and Togaviridae?

A
  1. Non-segmented (+) Strand RNA genome

2. Enveloped

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10
Q

List 3 Vaccines for Poiio

A
  1. Salk (killed)
  2. Sabin (live)
  3. eIPV (IgA)
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11
Q

Why does shock sydrome occur in Dengue fever?

A
  • Gets surrounded by antibodies
  • Macrophages eat virus and get infected
  • Cytokine surge
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12
Q

Name 2 types of Togavirus

A
  1. Alpha virus

2. Rubivirus

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13
Q

Since the poliovirus doesn’t need a ____ to replicate, it chops it in the host to promote its own growth solely

A

Cap

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14
Q

Corona Virus has a _____ nucleocapsid

A

Helical

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15
Q

Japanese and Saint Louis Encephalitis virus are both Flaviviruses that mainly target the children and eldery, a key therapuetic difference is that Japs have a _____ available

A

Vaccine

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16
Q

What type of Strand Sense is Polio virus?

A

Positive

17
Q

RNA viruses tend to stay in the _____, except for Influenza

A

Cytoplasm

18
Q

Of the Positive Strand viruses, what do Togaviridae, Flaviviridae, and Coronaviridae have in common?

A

Enveloped!

19
Q

Poliovirus is a prototypical ______virus

A

Picorna

20
Q

Plaque Assay makes _____ in cells

A

Holes

21
Q

Of the Positive Strand RNA viruses, what do Picornaviridae, Enterovirus, rhinovirus, Hepatovirus, and Caliciviridae have in common?

A

Non-Enveloped!

22
Q

Breakbone fever is also known as _____ Fever; has characteristic bone and joint pain

A

Dengue

23
Q

Togavirus and Flaviviridae both create vesicles and bud off of ____ membranes

A

Organelle

24
Q

Poliovirus endocytoses and Viral ____ gets across the membrane and binds to ribosomes in cytosol

A

RNA

25
Q

The rash for rubella starts on the _____

A

Face

26
Q

What type of vaccine was used to eliminate Rubella from the US in 2004?

A

Live attenuated (MMR)

27
Q

Why are there no vaccines for the Hepatitis C flavivirus?

A

Hyper-variable glycoproteins

28
Q

Rubivirus causes _____

A

Rubella