Clinical Hepatitis Flashcards

Dr. McAulliffe

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1
Q

If you’re scared of HBV for a child less than 1 yr, what do you do?

A

Give Human Globulin

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2
Q

How does Hepatitis A present?

A

Only Acute

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3
Q

For Chronic Hep B Virus infection, you would see persistence of _____ in serum

A

HBsAg

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4
Q

How can Hepatitis C be cured?

A

Direct acting Antivral Drugs

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5
Q

Serological diagnosis for Hep A is _____ _____

A

Anti-HAV, IgM

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6
Q

The best correlate in serum to indicate Hep B immunity is ______

A

Anti-HB (antibody to surface antigen)

  • makes sense since infection is marked by HBsAg
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7
Q

Hep a is part of the _____Virus Family

A

Picorna

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8
Q

What’s the Cure for HBV infection?

A

There is none

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9
Q

Hepatitis C is in the _____viridae family (Along with Yellow Fever and Dengue)

A

Flavi

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10
Q

HBeAg strongly correlates with level of ____ ____

A

Viral Replication

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11
Q

Immunity due to Hep B vaccination vs Natural infection difference

A
  • You only see + Anti-Core in Natural

- You see negative HBsAg in both

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12
Q

Glecaprevir, Voxilaprevir, and Pibrentasivir are Direct Acting Antivirals used to treat Hep C that do what that is special?

A

Target all serotypes

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13
Q

Unlike most Reverse Transcriptases, Hep B replicates ______ infecting the cell

A

Before

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14
Q

Vaccines exist for Hep ____ and Hep _____

A

A, B

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15
Q

Anti-_____ is the best way to Test Hepatitis C with 99% Sensitivity as well as testing for Liver Fibrosis

A

HCV

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16
Q

Hep C is _____ Srand _NA genome with open reading frame

A

Positive, RNA