Negative Strand RNA viruses Flashcards

Dr Schein

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1
Q

Trivalent contains ___, ___, ___, whereas Quadravalent influenza vaccines contain ___, ___, ___, ___,

A
  • A, A, B

- A, A, B, B

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2
Q

Main example of a ReoVirus?

A

Rotavirus

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3
Q

SA-Gal 2,3 linkage corresponds with ____ flu

A

Avian

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4
Q

Paramyxovirus has HA, N, and F that it uses to fuse and make its signature _____ Cells

A

Giant

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5
Q

Name the two Anti-flu drugs that block uncoating agents

A
  1. Amantadine

2. Rimantidine

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6
Q

The flu virus falls under the Negative Strand ______viridae

A

Orthomyxo

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7
Q

In addition to all the swelling that occurs with Mumps, it can also cause serious ______

A

Deafness

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8
Q

The RSV virus stands for ____ ____ ___

A

Respiratory Syncytial Virus

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9
Q

Mnemonic for measles?

A

Koplik the hunter spots the smooth weasel.

  • smooth bc no Neuramidase
  • Koplik Red Spots
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10
Q

_____ _____ Virs is the single most important cause of viral lower respiratory tract disease in infants and children

A

Respiratory Syncytial

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11
Q

SA-Gal 2,6 linkage corresponds with ____ flu

A

human

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12
Q

Reoviridae and Rotavirus are both _____ ____ RNA viruses

A

Double-Stranded

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13
Q

Orthomyxoviridae, Paramyxoviridae, Rhabdoviridae, Arenaviridae, Bunyaviridae, Filoviridae are all _____ Strand _____ viruses

A

Negative, RNA

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14
Q

Neuraminidase and Hemagglutinin are 2 main components of the ____ virus envelope

A

Flu

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15
Q

The main Rhabdoviridaie is _____ Virus

A

Rabies

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16
Q

Key physical characteristic of Respiratory Enteric Orphan Virus

A

2 Icosahedral Capsids

17
Q

If Mumps goes for the ears, then Measles goes for the _____ with Punctuate Keratitis (In addition to Giant Cell Pneumonia)

A

Eyes

18
Q

For Flu viruses, the M1 matrix components interacts with Glycoproteins, while the M2 component that:

A

Is an ion channel

19
Q

Classic histological presentation of Rabies?

A

Negri Body

20
Q

Key aspect about Rotavirus replication?

A

Outer coat degrades, while inner coat remain in tact

21
Q

Which virus causes Lassa fever and Hemoorrhagic gevers?

A

Lymphocytic Choriomeningitis Virus

22
Q

Rhabdoviridae is ___ Shaped with a helical nucleocapsid

A

Bullet

23
Q

Parainfluenza, Mumps, Measles, RSV, hMPV, Nipah and Hendra all fall under the Negative Strand ________viridae

A

Paramyxo

24
Q

The Anti-influenza Drugs, Amantadine and Rimantidine target the ______ _____ of the flu

A

Uncoating

25
Q

Swine flu has both ___ and ____ SA-Gal linkages

A

2,3; 2,6

26
Q

How do you remember the suffix for Neuraminidase inhibitors for Anti-Influenza Drugs

A

The Mivirs; block neuraMINidase

27
Q

Name the 2 main components of the Flu virus’s envelope

A
  1. Neuraminidase

2. Hemagglutinin

28
Q

Aside from having T-shaped proteins and GP1 and GP2, what’s special about the Arena Virus?

A

It can be read Ambisense!

29
Q

The key physical characterstic of RSV is it’s ______

A

NAKE (No Hemagg, Neuramini, or HN glycoprotin)

30
Q

Name the 2 Double Stranded RNA viruses

A
  1. Reoviridae

2. Rotavirus

31
Q

The Anti-influenza Drugs, Oseltamivir, Zanamivir, and Peramivir (The Mivirs) all inhibit the Envelope component ______

A

Neuraminidase

32
Q

The main Filoviridae is ____ Virus

A

Ebola