Gram Positive Rods

Question 1

Corynebacteriuum Diptheriae, Bacillus anthracis, Listeria Monocytogenes, and the Clostridiums (perf, botulin, tetani, difficlie, are all examples of Gram _____ _____

Answer 1

Positive Rods

Question 2

Of the Gram Positive rods, what do diphtheriae and Listeria have in common?

Answer 2

Non-spore forming

Question 3

Bacillus anthracis, bacillus cereus, and the Clostridiums all form _____

Answer 3

spores

Question 4

What does the Non-spore forming Propionbacterium Acnes share with the Spore-forming Clostridia?

Answer 4

They’re both Anaerobic!

Question 5

Diptheria makes _____-Toxin which inactivates _____ by ADP-ribosylating it.

Answer 5

EF-2 (Elongation Factor)

Question 6

Diptheria typically presents in throat and nasopharynx with the clinical distinction of a “bull-neck” _____ that forms

Answer 6

gray pseudomembrane

Question 7

Tinsdale’s agar and Postassium tellurite are both used to identify the Gram positive, club-shaped bacteria known as _____

Answer 7

Diphtheria

Question 8

What is special about Listeria’s pathogenesis?

Answer 8

It uses membrane-damaging-toxin and recreates actin to escape

Question 9

A gram-positive bacteria with tumbling motility would make you suspect _____

Answer 9

Listeria

Question 10

Anthrax’s 2 main toxins

Answer 10

1. Edema Factor

2. Lethal Toxin

Question 11

If you see Non-motile Endospores with Gram positive bacilli and a COMMA SHAPE, you should suspect

Answer 11

Anthrax

Question 12

If you see air in muscle from decay, you would suspect Clostridium _____ causing Myonecrosis

Answer 12

Perfringens

Question 13

What gram positive spore-producing bacteria produces Alpha-toxin, causes “gas gangrene” and a double zone of hemolysis?

Answer 13

Clostridium Perfringens

Question 14

The Botulinum toxin chops the _____ proteins, not allowing Ach vesicles to dock and fuse

Answer 14

SNARE

Question 15

Tetanus toxin blocks neurotransmitter release at _____ synapses

Answer 15

Inhibitory

Question 16

C. diff inactivates _____ family proteins

Answer 16

Rho

Question 17

Anthrax’s 2 main Toxins Edema Factor (EF) and Lethal Factor (LF) both bind to ________ before entering cells. Antibodies to this are protective against the toxic effects of EF and LF

Answer 17

Protective Antigen (PA)

Question 18

What makes culturing Clostridia difficult?

Answer 18

They’re Anaerobic

Question 19

If you give an infant honey, they risk getting ______

Answer 19

botulism

Question 20

Botulin vs Tetanus

Answer 20

Botulin = Flaccid
Tetanus = Spastic

Question 21

Clostridium Perfingen’s Blood agar clinical Identifier?

Answer 21

Double Zone of Beta-Hemolysis