Antiviral drugs Flashcards

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1
Q

Sofosbuvir is a _____ analog

A

Uridine

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2
Q

To treat Hep C name 4 drugs that block NS5A

A
  1. Ledi
  2. Velpa
  3. Pibre
  4. Elbasvir
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3
Q

Enfurvirtide, Maraviroc, and Ibalizumab are all ___ ____ inhoibitors

A

Viral Fusion

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4
Q

The HIV drug Ibalizumab blocks _______

A

CD4

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5
Q

Emtricitabine and Tenofovir are Nucleoside Analogs that inhibit the enzyme _____ _____

A

Reverse Transcriptase

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6
Q

3 Drugs to treat Cytomegalovirus

A
  1. Valcicolvir
  2. Ganciclovir
  3. Letermovir
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7
Q

Letermovir treats CMV by inhibit the _______ _____

A

DNA cleavers

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8
Q

Valgan, Gan, and Letermovir all treat the disease _____

A

Cytomegalovirus

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9
Q

2 mRNA cap-snatching drugs

A
  1. Baloxavir

2. Marboxil

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10
Q

Ledi, Velpa, Pibre, and Elbasvir all inhibit the structural enzyme ________ to treat Hep C

A

NS5A

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11
Q

Hepatits’ C’s NS5B function

A

Rnaa-Dependent-Rna polymerase

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12
Q

Suffix to remember the M2 flu inhibitors?

A

“mantas”

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13
Q

Suffix to remember NeuraMINidase inhibitors?

A

“mivirs”

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14
Q

Baloxavir and Marboxil both inhibit ______ _____ ____

A

mRNA Cap-Snatching

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15
Q

Sofosbuvir, Glecaprevir, Grazoprevir, Voxilprevir, Ledisvir, Velpasivr, Pibrevvir, and Elbasvir all treat Hepatitis _____

A

C

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16
Q

Truvada is made up of two Nucleoside analogs, which are they?

A
  1. Emtricitabine

2. Tenofovir-Diso

17
Q

Doravirine:

A

Non-Nucleoside reverse transcriptase inhibitor that binds at the allosteric site

18
Q

Valgan and Ganciclovir are processed by ______

A

UL97

19
Q

To treat HIV you would use which 4 drugs to work as Integrase inhibitors?

A
  1. Raltegravir
  2. Elvitgravir
  3. Dolutgravir
  4. Bictegravir
20
Q

Interferon, Tenofvir, and Entecavir all treat Hepatitis ____

A

B

21
Q

To treat Hepatitis C, the -“_____”s (suffix) block NS3/4A protease

A

Previr

22
Q

2 Main Reverse Transcriptase Nucleoside Analogs

A
  1. Emtricitbaine

2. Tenofovir

23
Q

Sofosbuvir blocks the enzyme _____ to treat Hep C

A

NS5B

24
Q

The 2 flu M2 blockers

A
  1. Amantadine

2. Rimantadine

25
Q

Gleca, Grazo, and Voxilprevir all inhibit ______

A

NS3/4A protease

26
Q

Main Non-Nucleoside RTI is ____

A

Doravirine

27
Q

The HIV drug Enfuvirtide blocks ___

A

Gp41

28
Q

Out of the HIV drugs Darunavir is the only one that inhibits the enzyme _____

A

Protease

29
Q

Zanamivir, Osetlamivir, and Peramivir are all _____ inhibitors

A

Neuraminidase

30
Q

Acyclovir needs to be processed by the Viral enzyme _____ _____

A

Thymidine Kinase

31
Q

Ralte, Elvit, Dolut, and Bictegravir are all _______ inhibitors

A

Integrase

32
Q

3 Drugs to treat Hep B

A
  1. IFN
  2. Tenofovir
  3. Entecavir
33
Q

Acyclovir and Ganciclovir are both _____ Derivatives

A

Guanosine

34
Q

The HIV drug Maraviroc blocks _____

A

CCR5