Antibiotic Agents Flashcards
Dr. Pilch
The only bactericidal protein synthesis inhibitor are the _____ class of antibiotics because of their postantibiotic effect
Aminoglycosides
Streptomycin, Gentamicin Tobramycin, Amikacin, Neomycin, Kanamycin are all examples of _____ that inhibit 30S
Aminoglycosides
Tobramycin and Gentamicin are really good against Gram _____ bacteria
Negative
Of the Aminoglycosides, Neomycin and Kanamycin are only used on _____ surfaces
Topical
The biggest problem with the Aminoglycosides are that they are _____ as well as Ototoxicity
Nephrotoxic
Tetracyclines block the _____ step of protein synthesis by targeting the Aminoacyl tRNAs
Elongation
All drugs that end in “Cycline” belong to the class known as _____
Tetracyclines
When you’re taking a Tetracycline you should avoid taking _____
Dairy/Calcium
Rickettsial infections and STDs are typically treated with the _____ class of antibiotics
Tetracyclines
Tigecycline and Eravacycline are glycylcylines reserved for _____ infections
MRSA
The two antibiotic inhibitors of the 30S Ribosomal Subunit are _____ and _____
Aminoglycosides, Tetracyclines
Macrolides, Lincosamides, Streptogramins, and Oxazolidinones are all inhibitors of the ______S Ribosomal Subunit
50
The Macrolides are great for treating _____ infections
Respiratory
The Lincosamide, Clindamycin works only against Gram-_____ bacteria
Positive
What class of antibiotics is Azithromycin?
Macrolides
Sulfonamides Trimethoprim are DNA synthesis inhibitors that specifically block ______
Folate
Fluoroquinolones are the newest classes of antibiotics that target _____ and _____
Gyrase and Topoisomerase
What’s special about Sulfonamides and Timethoprim?
They block successive steps in folic acid synthesis and actually wreck bacteria together.
Unlike mammals, Sulfonamide-susceptible microorganisms cannot use exogenous folate, but must synthesize it from _____ _____
p-aminobenzoic acid
The “oxacins” are the ______ antibiotics that are bactericidal
Fluorquinones
