Antibiotic Agents

Question 1

The only bactericidal protein synthesis inhibitor are the _____ class of antibiotics because of their postantibiotic effect

Answer 1

Aminoglycosides

Question 2

Streptomycin, Gentamicin Tobramycin, Amikacin, Neomycin, Kanamycin are all examples of _____ that inhibit 30S

Answer 2

Aminoglycosides

Question 3

Tobramycin and Gentamicin are really good against Gram _____ bacteria

Answer 3

Negative

Question 4

Of the Aminoglycosides, Neomycin and Kanamycin are only used on _____ surfaces

Answer 4

Topical

Question 5

The biggest problem with the Aminoglycosides are that they are _____ as well as Ototoxicity

Answer 5

Nephrotoxic

Question 6

Tetracyclines block the _____ step of protein synthesis by targeting the Aminoacyl tRNAs

Answer 6

Elongation

Question 7

All drugs that end in “Cycline” belong to the class known as _____

Answer 7

Tetracyclines

Question 8

When you’re taking a Tetracycline you should avoid taking _____

Answer 8

Dairy/Calcium

Question 9

Rickettsial infections and STDs are typically treated with the _____ class of antibiotics

Answer 9

Tetracyclines

Question 10

Tigecycline and Eravacycline are glycylcylines reserved for _____ infections

Answer 10

MRSA

Question 11

The two antibiotic inhibitors of the 30S Ribosomal Subunit are _____ and _____

Answer 11

Aminoglycosides, Tetracyclines

Question 12

Macrolides, Lincosamides, Streptogramins, and Oxazolidinones are all inhibitors of the ______S Ribosomal Subunit

Answer 12

50

Question 13

The Macrolides are great for treating _____ infections

Answer 13

Respiratory

Question 14

The Lincosamide, Clindamycin works only against Gram-_____ bacteria

Answer 14

Positive

Question 15

What class of antibiotics is Azithromycin?

Answer 15

Macrolides

Question 16

Sulfonamides Trimethoprim are DNA synthesis inhibitors that specifically block ______

Answer 16

Folate

Question 17

Fluoroquinolones are the newest classes of antibiotics that target _____ and _____

Answer 17

Gyrase and Topoisomerase

Question 18

What’s special about Sulfonamides and Timethoprim?

Answer 18

They block successive steps in folic acid synthesis and actually wreck bacteria together.

Question 19

Unlike mammals, Sulfonamide-susceptible microorganisms cannot use exogenous folate, but must synthesize it from _____ _____

Answer 19

p-aminobenzoic acid

Question 20

The “oxacins” are the ______ antibiotics that are bactericidal

Answer 20

Fluorquinones