Viral Structure

Question 1

5 things that define virus

Answer 1

Infectious, obligate, intracell parasite
DNA or RNA genetic material
Genetic material will direct productions of new virus particles (virions)
New virions made in host cell
New virions produced in host cell and then trasnport genetic material to another host cell

Question 2

All viruses have

Answer 2

Capsid (surrounds nucleic acid)

Question 3

Spikes

Answer 3

Glycoproteins that mediate attachment (tropism)

Question 4

Enveloped virus

Answer 4

Has envelope derived from a host cell…the envelope is where the spikes are attached

Question 5

All viruses must

Answer 5

produce mRNA that can be read and translated by host cell ribosomes

Question 6

Viral classifcation mostly based on

Answer 6

Genetic material and whether naked or enveloped

Question 7

Hep viruses classifications

Answer 7

C - ssRNA+ enveloped
E and A - SSRNA+ naked
B - dsDNA enveloped

Question 8

Hep viruses transmission and why

Answer 8

A and E fecal
B and C blood borne

Fecal are naked…capsule is stable and can survive the GI tract…envelope derived from hepatocytes cannot survive the GI tract…envelope contained the spikes so it can’t attach