Vaccines Flashcards
What is a vaccine?
contains antigens to stimulate an immune response
could be from a dead/attenuated pathogen
mRNA vaccine - codes for antigen and makes immune response
What do vaccines do?
antigen is displayed on the surface of antigen presenting cells e.g. phagocytes
specific t cells with complimentary receptor binds to the presented antigen
activates bcells with complimentary antibody
b cells form many cloans (divide by mitosis to make more plasma cells)
plasma cells make antibodies
some t cells and b cells develop into memory cells
What happens when vaccines stimulate primary immune response and secondary response?
when a pathogen infects us, we will already have the t cells and memory b cells
go through secondary immune response
dont feel symptoms
vaccines are artificial active immunity
injected (not taken orally) - stomach acid and digestive enzymes will hydrolyse the antigen and too large to be absorbed