Vaccination in Pregnancy TOG Flashcards

1
Q

what is the main immunoglobulin found in breastmilk?

A

Ig A

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2
Q

what are the 3 main types of vaccines, and which are safe in pregnancy?

A

live vaccines
killed vaccines
purified macromolecules..

Killed and purified macromolecules are safe in pregnancy- toxoids, inactivated virus vaccines, immune globulin preparations.

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3
Q

which trimester is safest for vaccines to be given?

A

second trimester

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4
Q

which vaccines are routinely offered to all pregnant women in the UK?

A
B. pertussis
Diptheria
Tetanus
Polio
Inactivated Influenza
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5
Q

at what gestation should the influenza vaccine be given?

A

Any gestation (1st, 2nd, 3rd tri). Influenza vaccinations are usually given btwn Oct-Jan.

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6
Q

When should pregnant women receive the B. pertussis vaccine?

A

between 28/40-38/40

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7
Q

When should pregnant women receive the tetanus/diptheria/polio vaccine?

A

between 28-38/40. ideally between 28-32/40

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8
Q

what is the purpose of immunising pregnant women against whooping cough?

A

boost antibodies so that they are passed to baby. This should protect the infant until it is vaccinated at 2 months age.

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9
Q

Which specific vaccines are contraindicated in pregnancy?

A
BCG
MMR
Varicella
Vaccinia
HPV
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10
Q

If a woman has recently had MMR vaccine, for how long should she avoid pregnancy?

A

28 days

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11
Q

if the children of a pregnant woman have recently been vaccinated with MMR, are the children infective?

A

No. Infection is not transmitted from recently immunised individuals

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12
Q

If a non-pregnant woman has chicken pox vaccine, how long should she wait to get pregnant?

A

4 weeks.

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13
Q

Under what circumstances would women be offered vaccination against Hep A?

A
long term liver disease
haemophilia
IVDU
working with/near sewage
institutions where personal hygiene may be poor
working with primates
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14
Q

what type of vaccine is Hep B vaccine?

A

inactivated sub-unit vaccine

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15
Q

which women are at high risk of Hep B and therefore should be offered Hep B vaccine?

A
woman or partner injects drugs
multiple sex partners
woman who is close family/sex partner of someone with Hep B
woman receives regular blood transfusion
liver disease, CKD
travelling to high risk countries
sex workers
exposed to bodily fluids (dr, nurse, dentists, lab staff)
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16
Q

what risk factors would lead you to offer a woman vaccination against meningococcus?

A
functional/anatomical asplenia
immunosuppression
complement deficiency
travel to high-risk endemic areas
contact with infected individuals
university students under age 25
17
Q

what indications are there for administering pneumococcal conjugated vaccine to women?

A

functional/ anatomical asplenia
sickle cell disease
splenectomy
HIV

18
Q

which vaccines are safe in breastfeeding?

A

inactivated, recombinant, subunit, polysaccharide, conjugated, toxoids

19
Q

which vaccine, specifically, should be avoided in breast-feeding, but can be considered in pregnancy?

A

yellow fever

20
Q

what is the vaccination course/administration for VZV?

A

2 doses, 4-8 weeks apart. Avoid pregnancy for 1/12 after each dose