Vaccination in Pregnancy TOG Flashcards
what is the main immunoglobulin found in breastmilk?
Ig A
what are the 3 main types of vaccines, and which are safe in pregnancy?
live vaccines
killed vaccines
purified macromolecules..
Killed and purified macromolecules are safe in pregnancy- toxoids, inactivated virus vaccines, immune globulin preparations.
which trimester is safest for vaccines to be given?
second trimester
which vaccines are routinely offered to all pregnant women in the UK?
B. pertussis Diptheria Tetanus Polio Inactivated Influenza
at what gestation should the influenza vaccine be given?
Any gestation (1st, 2nd, 3rd tri). Influenza vaccinations are usually given btwn Oct-Jan.
When should pregnant women receive the B. pertussis vaccine?
between 28/40-38/40
When should pregnant women receive the tetanus/diptheria/polio vaccine?
between 28-38/40. ideally between 28-32/40
what is the purpose of immunising pregnant women against whooping cough?
boost antibodies so that they are passed to baby. This should protect the infant until it is vaccinated at 2 months age.
Which specific vaccines are contraindicated in pregnancy?
BCG MMR Varicella Vaccinia HPV
If a woman has recently had MMR vaccine, for how long should she avoid pregnancy?
28 days
if the children of a pregnant woman have recently been vaccinated with MMR, are the children infective?
No. Infection is not transmitted from recently immunised individuals
If a non-pregnant woman has chicken pox vaccine, how long should she wait to get pregnant?
4 weeks.
Under what circumstances would women be offered vaccination against Hep A?
long term liver disease haemophilia IVDU working with/near sewage institutions where personal hygiene may be poor working with primates
what type of vaccine is Hep B vaccine?
inactivated sub-unit vaccine
which women are at high risk of Hep B and therefore should be offered Hep B vaccine?
woman or partner injects drugs multiple sex partners woman who is close family/sex partner of someone with Hep B woman receives regular blood transfusion liver disease, CKD travelling to high risk countries sex workers exposed to bodily fluids (dr, nurse, dentists, lab staff)