Maternal medicine - Neurological Disorders

Question 1

What percentage of women of childbearing age have Epilepsy?

Answer 1

0.5%

Question 2

What percentage of pregnancies are complicated by Epilepsy?

Answer 2

3.5%

Question 3

What is the risk of a child developing Epilepsy if:
Maternal epilepsy?
Both parents have Epilepsy?
Older sibling has Epilepsy?

Answer 3

Maternal Epilepsy - 4-5%
Both parents - 15-20%
Affected sibling - 10%

Question 4

True or false - women affected by antiphospholipid syndrome have an increased risk of epilepsy.

Answer 4

True

Question 5

What percentage of women continue to be seizure free if they haven’t had a seizure for at least 9months to a year prior to pregnancy?

Answer 5

74-92%

Question 6

Epilepsy is an indirect cause of maternal mortality. What is the maternal mortality rate?

Answer 6

5-10 per million mortalities

5 cases a year in the Uk

Question 7

What are the risk factors for Sudden unexplained death in Epilepsy?

Answer 7

Increased seizure frequency
Low IQ
Early onset Epilepsy
Multiple antiepileptic drugs

Question 8

What is the risk of major congenital malformation in the fetus of a mother with epilepsy?

Answer 8

4-10%

Background risk of major congenital abnormalities is 2-3%