uworld9

Question 1

zofran MOA

Answer 1

serotonin receptor antagonists

Question 2

fungus ball. think

Answer 2

aspergillosis

Question 3

chronic pulmonary aspergillosis presentation

Answer 3

> 3 months: weight loss, cough, hemoptysis, fatigue

in patients with underlying lung dz

Question 4

which kidney nephritic/nephrotic syndrome is caused by IgG antibodies directed against C3 convertase of the alternative complement pathway?

Answer 4

membranoproliferative glomerulonephritis (aka dense deposit disease)

has proteinuria and hematuria

Question 5

most common hereditary hypercoagulable disorder among white people

Answer 5

factor V leiden (protein C resistance)

Question 6

antithrombin deficiency

Answer 6

acquired- in setting of DIC, cirrhosis, nephrotic syn

Question 7

how to treat post-nasal drip induced asthma?

Answer 7

H1 blocker

Question 8

which arrythmia does digitalis toxicity produce?

Answer 8

atrial tachycardia with AV block

Question 9

S4 is a stiffened ventricle from

Answer 9

prolonged HTN

Question 10

when is passive immunity tetanus antibodies given?

Answer 10

• if SYMPTOMATIC tetanus

- got a dirty wound but has not received the 3 childhood vaccines

Question 11

what to give if adult who had the childhood vaccines gets a wound from a rusty nail?

Answer 11

Tdap vaccine

Question 12

continuous abdominal bruit is indicative of

Answer 12

renovascular disease (renal artery stenosis)

Question 13

common causes of esophagitis in HIV patient

Answer 13

candida- white plaques

HSV- round ulcers

CMV- deep linear ulcers

apthous ulcesr

Question 14

drug of choice to stabilize bony metastatic lesions to prevent hypercalcemia of malignancy

Answer 14

bisphosphonates

Question 15

someone with pancreatitis gets lung issues and bilateral opacities. think…

Answer 15

ARDS

Question 16

management of ARDS

Answer 16

low tidal volume ventilation- dont overdistend alveoli

oxygenate with PEEP to goal of SpO2 88-95%

Question 17

chronic lymphocytic leukemia diagnosed how

Answer 17

flow cytometry- showing clonality of mature B celsl

Question 18

treat bulimia’s metabolic alkalosis

Answer 18

normal saline infusion

Question 19

graft versus host dz is usually donor or host attacking?

Answer 19

donor T cells

Question 20

organs typically affected by graft v host dz

Answer 20

skin- maculopapular rash
intestine- dirarrhea
liver- jaundice, abnl tests

Question 21

characteristics of pulmonic stenosis

Answer 21

LUSB
ejection click, cresc-decrescendo systolic murmur
widened split of S2

congenital
asx till adulthood

Question 22

initial therapy for peripheral artery disease

Answer 22

ASA, statin
exercise therapy

try above before cilostazol or stents

Question 23

how long of IV abx for uncomplicated pyelonephritis before oral?

Answer 23

2 days

Question 24

which parasite– causes hyatid cysts- hepatic cyst with daughter cysts (internall septations)

Answer 24

echinococcus