uworld16

Question 1

sxs of mycoplasma

Answer 1

pneumonia (cough, fever, malasie, HA)

pharyngitis

macular rash

subclinical cold hemolytic anemia

young people!

Question 2

what to do if you get poked with HIV blood

Answer 2

3 antiretrovirals immediately for 1 month (tenofovir-emtracitabine with raletgavir)

Question 3

which dz? cortical thickening of femur, inc alk phos, hearing loss, HA, spinal stenosis, frontal bossing

Answer 3

paget disease of the bone

Question 4

where does RA affect in the spine?

Answer 4

cervical spine

Question 5

how does thyrotoxicosis cause HTN, arrythmias, widened pulse pressure

Answer 5

increased sensitivity to catecholamines –> increased HR and contractility

Question 6

isolated systolic HTN is caused by

Answer 6

stiffness of arterial wall

Question 7

which dz? fever, arthralgias, glomerulonephritis, painful fingertips, valvular insufficiency/SOB, positive RF

Answer 7

infective endocarditis

Question 8

which dz? back pain radiating down thighs bilaterally worse with standing and exertion, relieves with leaning over

Answer 8

lumbar spinal stenosis

Question 9

sciatica

Answer 9

lumbar disc herniation –> unilateral radiation

flexion makes it worse

Question 10

treatment for central diabetes insipidus

Answer 10

desmopressin

Question 11

demeclocycline treats which dz

Answer 11

SIADH- inhibits ADH aquaporin

Question 12

treatment for nephrogenic diabetes insipidus

Answer 12

hydrochlorothiazide

Question 13

tolvaptan MOA and use

Answer 13

V2 vasopressin rec antagonist

used for refractory hyponatremia (SIADH)

Question 14

which dz? fibrotic lung, arthralgias, esophageal dysmotility

Answer 14

systemic sclerosis

Question 15

physiology of ARDS

Answer 15

VQ mismatch- gas exchange impaired

decreased lung compliance

pulm HTN

Question 16

peripheral neuropathy by isoniazid is caused by what

Answer 16

vit B6 (pyridoxine) def

Question 17

which dz? x rays of knee joint show punched out erosions of bone with a rim of cortical bone

Answer 17

gout

Question 18

someone with PMHx of hodgkin lymphoma treated with chemo/RT develops mass on CXR. what is it?

Answer 18

secondary malignancy

Question 19

euthyroid conditions that increase thyroid binding globulin (TBG)

Answer 19

estrogens (pregnancy, OCPs)

hepatic dysfunction

meds- tamoxifen

Question 20

euthyroid conditions that decrease TBG?

Answer 20

hormonal- cushings, steroids

low protein- nephrotic syn, starvation

meds- niacin, androgens

Question 21

does T4 increase or decrease with an increase in TBG?

Answer 21

increases to maintain euthyroid state (because only free is active, and body tries to maintain itself)