uworld16 Flashcards
sxs of mycoplasma
pneumonia (cough, fever, malasie, HA)
pharyngitis
macular rash
subclinical cold hemolytic anemia
young people!
what to do if you get poked with HIV blood
3 antiretrovirals immediately for 1 month (tenofovir-emtracitabine with raletgavir)
which dz? cortical thickening of femur, inc alk phos, hearing loss, HA, spinal stenosis, frontal bossing
paget disease of the bone
where does RA affect in the spine?
cervical spine
how does thyrotoxicosis cause HTN, arrythmias, widened pulse pressure
increased sensitivity to catecholamines –> increased HR and contractility
isolated systolic HTN is caused by
stiffness of arterial wall
which dz? fever, arthralgias, glomerulonephritis, painful fingertips, valvular insufficiency/SOB, positive RF
infective endocarditis
which dz? back pain radiating down thighs bilaterally worse with standing and exertion, relieves with leaning over
lumbar spinal stenosis
sciatica
lumbar disc herniation –> unilateral radiation
flexion makes it worse
treatment for central diabetes insipidus
desmopressin
demeclocycline treats which dz
SIADH- inhibits ADH aquaporin
treatment for nephrogenic diabetes insipidus
hydrochlorothiazide
tolvaptan MOA and use
V2 vasopressin rec antagonist
used for refractory hyponatremia (SIADH)
which dz? fibrotic lung, arthralgias, esophageal dysmotility
systemic sclerosis
physiology of ARDS
VQ mismatch- gas exchange impaired
decreased lung compliance
pulm HTN
peripheral neuropathy by isoniazid is caused by what
vit B6 (pyridoxine) def
which dz? x rays of knee joint show punched out erosions of bone with a rim of cortical bone
gout
someone with PMHx of hodgkin lymphoma treated with chemo/RT develops mass on CXR. what is it?
secondary malignancy
euthyroid conditions that increase thyroid binding globulin (TBG)
estrogens (pregnancy, OCPs)
hepatic dysfunction
meds- tamoxifen
euthyroid conditions that decrease TBG?
hormonal- cushings, steroids
low protein- nephrotic syn, starvation
meds- niacin, androgens
does T4 increase or decrease with an increase in TBG?
increases to maintain euthyroid state (because only free is active, and body tries to maintain itself)
