UWorld toxic epidermal necrolysis Flashcards

1
Q

cushing syndrome

A

htn
hyperglycemia
wt gain

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2
Q

What thyroid pathology has psammoma bodies

A

papillary thyroid cancer

*most common thyroid pathology

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3
Q

MEN 1 features

A

pituitary adenoma
primary hyperparathyroidism
pancreatic/GI neuroendocrine tumors

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4
Q

Rx for dermatitis herpetiformis

A

dapsone

d/c gluten

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5
Q

When do you intubate a COPD exaserbation

A

AMS
acidemia < 7.1
hemodynamic instability

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6
Q

angiodysplasia

A

dilated veins/ AVMs

common cause of painless GI bleed

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7
Q

reversible causes of ua incontinence in old people

A
delirium
infection- uti
atrophic urethritis 
pharm- drugs
psych 
excessive ua- t2dm
restricted mobility
stool impaction
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8
Q

Rx for human bite

A

amoxicillin-clavulanate

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9
Q

Prolonged infusion of sodium nitroprusside can lead to __________ toxicity

A

cyanide

esp in pts w/ CKD

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10
Q

CD4 count under 200 prophylaxis

A

Tmp-Smx

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11
Q

what does good glucose control actually help?

A

microvascular disease

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12
Q

CD4 count under 50 prophylaxis

A

azithromycin- mac
itraconazole- histo
tmp-smx- PCP, toxo

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13
Q

What is a general good A1C goal

A

7-8%

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14
Q

seborrheic dermatitis

A

yellow scale on red base
scalp/ face
itchy
topical antifungals help

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15
Q

stable pt in a-fib gets?

A

beta blocker
diltiazem
digoxin

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16
Q

hemodynamically unstable pt in afib gets?

A

cardioversion

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17
Q

best indicators for rx of DKA

A

serum anion gap

beta-hydroxybutyrate

18
Q

complications of positive pressure ventilation

A

alveolar damage
pneumothorax
hypotension

19
Q

Acute intermittent porphyria

A

severe abdominal pain
patchy sensorimotor neuropathy
autonomic dysfunction

20
Q

Lead poisoning

A

stocking glove neuropathy
microcytic anemia
GI upset

21
Q

arsenic toxicity

A

painful sensorimotor neuropathy
skin lesions
pancytopenia
↑ LFTs

22
Q

Best cosmetic way to remove basal cell carcinoma

A

mohes

remove thin layers examining each for tumor margin

23
Q

What do you avoid giving in RV MI

A

nitrates
diuretics

*you DO NOT want to ↓↓ preload

24
Q

Rx for boulos pemphigoid

A

topical clobetasol

25
Q

colonoscopy in laxative abuse

A

melanosis coli (dark brown discoloration)

26
Q

First line Rx for BPH

A

alpha 1 blocker

faster onset than 5-alpha reductase inhibitors

27
Q

porphyria cutanea tarda

A

most common porphyria
deficiency of uroporphyinogen decarboxylase
asc. w/ hep c
s/s photosensitivity and fragile skin

28
Q

How long after an MI does papillary muscle rupture occur?

A

2-7 days

29
Q

What may have happened after an MI if the ST elevation persists 3 months later?

A

Ventricular aneurysm

30
Q

Lung disease in ank spon

A

restrictive from ↓ chest wall motion

31
Q

Morton neuroma

A

common in runners
nerve degeneration–> paresthesia/ pain
rx: foot support/ pad

32
Q

What looks just like mono (mostly)?

A

CMV mono
fever, malaise, atypical lymphs

NO pharyngitis or splenomegaly

33
Q

D-xylose test

A

malabsorption test- but no enzymes needed

if normal= excreted in ua

if malabsorption= low amount in UA, indicates small bowel mucosal disease

34
Q

most common cause of acquired angioedema

A

ACE inhibitor side effect

35
Q

Paroxysmal nocturnal hemoglobinuria

A

hemolytic anemia
cytopenia
hyper coagulable

*missing CD55 and CD59

36
Q

Nocardia Rx

A

tmp-smx

37
Q

jarisch herxheimer rxn

A

acute febrile illness <12 hours after syphilis rx

38
Q

what comorbidity should you test all “pseudogout” people for

A

hemochromatosis

39
Q

Isoniazid s/e that mimics a virus

A

hepatic injury

looks like viral hepatitis on biopsy

40
Q

VIPoma

A

pancreatic tumor

s/s water diarrhea, muscle cramps (hypokalemia)

41
Q

Uric acid stone prevention

A

↑ fluids

oral potassium citrate